(Q22010915)

negative regulation of calcineurin-NFAT signaling cascade

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

X Lin

1

X

Lin

1 reference

7 February 2023

R A Sikkink

series ordinal

2

author given names

R A

author last names

Sikkink

1 reference

7 February 2023

F Rusnak

series ordinal

3

author given names

F

author last names

Rusnak

1 reference

7 February 2023

D L Barber

series ordinal

4

author given names

D L

author last names

Barber

1 reference

7 February 2023

language of work or name

English

0 references

publication date

17 December 1999

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published in

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volume

274

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page(s)

36125-31

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issue

51

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cites work

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody

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Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

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Identification of a putative regulator of early T cell activation genes

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FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

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Immunophilin-sensitive protein phosphatase action in cell signaling pathways

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A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange

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A novel Ca2+-binding protein, p22, is required for constitutive membrane traffic

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Calcium, calmodulin and cell cycle regulation

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Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin.

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Three-dimensional structure of calmodulin

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Structure of calmodulin refined at 2.2 A resolution

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X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

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Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

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Attachment of A172 human glioblastoma cells affects calcium signalling: a comparison of image cytometry, flow cytometry, and spectrofluorometry

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Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B

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Calcineurin subunit interactions: mapping the calcineurin B binding domain on calcineurin A.

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The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

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Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

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Characterization of a cDNA clone encoding the calmodulin-binding domain of mouse brain calcineurin

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Interaction of FKBP12-FK506 with calcineurin A at the B subunit-binding domain

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Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes

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Cain, a novel physiologic protein inhibitor of calcineurin

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AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

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A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

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Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

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Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin

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Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

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Calcineurin acts in synergy with PMA to inactivate I kappa B/MAD3, an inhibitor of NF-kappa B.

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7 January 2021

The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation

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7 January 2021

Regulation of calcium-induced exocytosis from gastric chief cells by protein phosphatase-2B (calcineurin)

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7 January 2021

Control of the alpha 5 beta 1 integrin/fibronectin interaction in vitro by the serine/threonine protein phosphatase calcineurin

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https://api.crossref.org/works/10.1074%2FJBC.274.51.36125

7 January 2021

Functional domain structure of calcineurin A: mapping by limited proteolysis

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https://api.crossref.org/works/10.1074%2FJBC.274.51.36125

7 January 2021

Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506.

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https://api.crossref.org/works/10.1074%2FJBC.274.51.36125

7 January 2021

Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth

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7 January 2021