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Transcriptional mechanisms of drug addiction
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scholarly article
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title
Transcriptional mechanisms of drug addiction
(English)
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main subject
substance dependence
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author
Eric J. Nestler
series ordinal
1
object named as
Eric J Nestler
author given names
Eric J
author last names
Nestler
1 reference
stated in
PubMed
PubMed ID
23430970
retrieved
7 February 2023
language of work or name
English
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publication date
December 2012
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published in
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
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stated in
PubMed
volume
10
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issue
3
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page(s)
136-43
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copyright license
Creative Commons Attribution-NonCommercial 3.0 Unported
start time
28 December 2012
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stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
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cites work
Transcriptional and epigenetic mechanisms of addiction
1 reference
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PubMed Central
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19 March 2017
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins
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PubMed Central
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19 March 2017
Phosphorylation of DeltaFosB mediates its stability in vivo
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PubMed Central
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19 March 2017
Review. Transcriptional mechanisms of addiction: role of DeltaFosB
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PubMed Central
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19 March 2017
Distinct patterns of DeltaFosB induction in brain by drugs of abuse
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PubMed Central
reference URL
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19 March 2017
Synaptic plasticity and addiction
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PubMed Central
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19 March 2017
Transcriptional regulation by the phosphorylation-dependent factor CREB
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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19 March 2017
Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure
1 reference
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PubMed Central
reference URL
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19 March 2017
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5
1 reference
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PubMed Central
reference URL
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19 March 2017
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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7 April 2017
Molecular basis of long-term plasticity underlying addiction
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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7 April 2017
The many faces of CREB
1 reference
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PubMed Central
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7 April 2017
Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Molecular and genetic substrates linking stress and addiction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Cocaine regulates MEF2 to control synaptic and behavioral plasticity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
CREB modulates the functional output of nucleus accumbens neurons: a critical role of N-methyl-D-aspartate glutamate receptor (NMDAR) receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Dimerization and DNA-binding properties of the transcription factor DeltaFosB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Structural plasticity associated with exposure to drugs of abuse
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Regulation of gene expression and cocaine reward by CREB and ΔFosB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Molecular neurobiology of addiction
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Regulation of cocaine reward by CREB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
12 September 2017
FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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12 September 2017
Physiological functions for brain NF-kappaB.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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27 September 2017
Immediate-early genes: ten years on.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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27 September 2017
A silent synapse-based mechanism for cocaine-induced locomotor sensitization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
30 May 2018
Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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30 May 2018
Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
30 May 2018
Sensitization to the behavioral effects of cocaine: modulation by dynorphin and kappa-opioid receptor agonists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
30 May 2018
Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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30 May 2018
Induction of activating transcription factors (ATFs) ATF2, ATF3, and ATF4 in the nucleus accumbens and their regulation of emotional behavior.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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29 November 2018
Proteasome-dependent and -independent mechanisms for FosB destabilization: identification of FosB degron domains and implications for DeltaFosB stability.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
Induction of inducible cAMP early repressor expression in nucleus accumbens by stress or amphetamine increases behavioral responses to emotional stimuli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
Regulation of DeltaFosB stability by phosphorylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
CREB modulates excitability of nucleus accumbens neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
An essential role for DeltaFosB in the nucleus accumbens in morphine action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
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29 November 2018
Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
Induction of nuclear factor-kappaB in nucleus accumbens by chronic cocaine administration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
Methamphetamine-induced increase in striatal NF-kappaB DNA-binding activity is attenuated in superoxide dismutase transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569166
retrieved
29 November 2018
Altered sensitivity to rewarding and aversive drugs in mice with inducible disruption of cAMP response element-binding protein function within the nucleus accumbens
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23430970
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.9758%2FCPN.2012.10.3.136
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.9758/CPN.2012.10.3.136
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1955386
OpenCitations bibliographic resource ID
1955386
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1955386
PMCID
3569166
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1955386
PubMed ID
23430970
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1955386
ResearchGate publication ID
235691524
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