(Q22252860)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18161758%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

review article

1 reference

title

Immune activation and inflammation in HIV-1 infection: causes and consequences (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18161758%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

1 reference

2

D Sauce

D

Sauce

1 reference

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31 December 2019

Appay V

1

V

Appay

1 reference

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31 December 2019

language of work or name

English

0 references

publication date

1 January 2008

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31 December 2019

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31 December 2019

volume

214

1 reference

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31 December 2019

issue

2

1 reference

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31 December 2019

page(s)

231-241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18161758%20AND%20SRC:MED&resulttype=core&format=json

CD8+ T-lymphocyte activation in HIV-1 disease reflects an aspect of pathogenesis distinct from viral burden and immunodeficiency.

31 December 2019

cites work

1 reference

CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

21 January 2018

1 reference

CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection.

21 January 2018

1 reference

Induction of telomerase activity and maintenance of telomere length in virus-specific effector and memory CD8+ T cells

21 January 2018

1 reference

The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.

21 January 2018

1 reference

The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines.

21 January 2018

1 reference

Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis

21 January 2018

1 reference

Frequencies of circulating cytolytic, CD45RA+CD27-, CD8+ T lymphocytes depend on infection with CMV.

21 January 2018

1 reference

Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion.

21 January 2018

1 reference

Bone mineral content is lower in prepubertal HIV-infected children.

21 January 2018

1 reference

Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study.

21 January 2018

1 reference

Frailty in older adults: evidence for a phenotype

21 January 2018

1 reference

The association of plasma IL-6 levels with functional disability in community-dwelling elderly

21 January 2018

1 reference

Serum IL-6 level and the development of disability in older persons

21 January 2018

1 reference

Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging.

21 January 2018

1 reference

Importance of age at infection with HIV-1 for survival and development of AIDS in UK haemophilia population. UK Haemophilia Centre Directors' Organisation

21 January 2018

1 reference

Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315.

21 January 2018

1 reference

Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy

21 January 2018

1 reference

Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors

21 January 2018

1 reference

7 January 2021

E5564 (Eritoran) inhibits lipopolysaccharide-induced cytokine production in human blood monocytes

1 reference

7 January 2021

Immune restoration inflammatory syndromes: apparently paradoxical clinical events after the initiation of HAART.

1 reference

7 January 2021

Thymic involution with ageing: obsolescence or good housekeeping?

1 reference

7 January 2021

Nitric oxide in the injured spinal cord: synthases cross-talk, oxidative stress and inflammation

1 reference

7 January 2021

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

1 reference

7 January 2021

Chronic antigenic load and apoptosis in immunosenescence

1 reference

7 January 2021

The multifactorial nature of HIV-1 latency

1 reference

7 January 2021

Ageing, immune response, and mortality

1 reference

7 January 2021

Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease

1 reference

7 January 2021

Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion?

1 reference

7 January 2021

Thymic atrophy in the mouse is a soluble problem of the thymic environment.

1 reference

7 January 2021

Age-associated thymic atrophy is linked to a decline in IL-7 production

1 reference

7 January 2021

The nitric oxide hypothesis of aging.

1 reference

7 January 2021

Biomarkers of immunosenescence within an evolutionary perspective: the challenge of heterogeneity and the role of antigenic load

1 reference

7 January 2021

Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators

1 reference

7 January 2021

Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

1 reference

7 January 2021

Premature ageing of the immune system: the cause of AIDS?

1 reference

7 January 2021

Chronic immune stimulation accelerates SIV-induced disease progression

1 reference

7 January 2021

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

1 reference

7 January 2021

Changes in thymic function with age and during the treatment of HIV infection

1 reference

7 January 2021

HIV preferentially infects HIV-specific CD4+ T cells

1 reference

7 January 2021

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

1 reference

7 January 2021

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

1 reference

7 January 2021

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

7 January 2021

1 reference

7 January 2021

HIV disease: fallout from a mucosal catastrophe?

1 reference

7 January 2021

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

7 January 2021

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

1 reference

7 January 2021

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 reference

7 January 2021

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

1 reference

7 January 2021

Ageing, tumour necrosis factor-alpha (TNF-alpha) and atherosclerosis

1 reference

7 January 2021

Comparison between HIV- and CMV-specific T cell responses in long-term HIV infected donors

1 reference

7 January 2021

Changes in calciotropic hormones and biochemical markers of bone metabolism in patients with human immunodeficiency virus infection

1 reference

7 January 2021

Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy

1 reference

7 January 2021

Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus

1 reference

7 January 2021

Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates

1 reference

7 January 2021

Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro

1 reference

7 January 2021

Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depleti

1 reference

7 January 2021

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

1 reference

7 January 2021

In vivo telomere dynamics of human hematopoietic stem cells

1 reference

7 January 2021

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

1 reference

7 January 2021

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals

1 reference

7 January 2021

Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse

1 reference

7 January 2021

Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.

1 reference

7 January 2021

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

1 reference

7 January 2021

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

1 reference

7 January 2021

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

1 reference

7 January 2021

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

1 reference

7 January 2021

Acute sexually transmitted infections increase human immunodeficiency virus type 1 plasma viremia, increase plasma type 2 cytokines, and decrease CD4 cell counts

1 reference

7 January 2021

Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors

1 reference

7 January 2021

Vaginal CD4+ T cells express high levels of CCR5 and are rapidly depleted in simian immunodeficiency virus infection

1 reference

7 January 2021

1 reference

7 January 2021

Bone disease and HIV infection

1 reference

7 January 2021

HIV infection and dementia in older adults

1 reference

7 January 2021

Cyclosporin A Provides No Sustained Immunologic Benefit to Persons with Chronic HIV‐1 Infection Starting Suppressive Antiretroviral Therapy: Results of a Randomized, Controlled Trial of the AIDS Clinical Trials Group A5138

1 reference

7 January 2021

CD8+CD38+ T cells but not HIV type 1 RNA viral load predict CD4+ T cell loss in a predominantly minority female HIV+ adolescent population.

1 reference

7 January 2021

Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process

1 reference

7 January 2021

Cell-mediated immunity as a predictor of morbidity and mortality in subjects over 60

1 reference

7 January 2021

HIV infection is associated with the spontaneous production off interleukin-1 (IL-1) in vivo and with an abnormal release off IL-1αaL in vitro

1 reference

7 January 2021

Increased interleukin-6 production is associated with disease progression in HIV infection

1 reference

7 January 2021

Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis.

1 reference

7 January 2021

Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone.

1 reference

7 January 2021

Reconstitution of naive T cells during antiretroviral treatment of HIV-infected adults is dependent on age.

1 reference

7 January 2021

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

1 reference

7 January 2021

Cognitive impairment in older HIV-1-seropositive individuals: prevalence and potential mechanisms

1 reference

7 January 2021

Aging and proinflammatory cytokines

1 reference

7 January 2021

Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count

1 reference

7 January 2021

PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status.

1 reference

7 January 2021

Cytomegalovirus (CMV) infection, CD4+ lymphocyte counts and the development of AIDS in HIV-1-infected haemophiliac patients

1 reference

7 January 2021

Thymic aging and T-cell regeneration

1 reference

7 January 2021

Programmed death of T cells in HIV-1 infection

1 reference

7 January 2021

Quantitative image analysis of HIV-1 infection in lymphoid tissue.

1 reference

7 January 2021

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4+ T Cell Turnover

1 reference

7 January 2021

Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease

1 reference

7 January 2021

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

7 January 2021

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1 reference

7 January 2021

1 reference

7 January 2021

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor.

1 reference

7 January 2021

Intestinal intraepithelial lymphocytes are primed for gamma interferon and MIP-1beta expression and display antiviral cytotoxic activity despite severe CD4(+) T-cell depletion in primary simian immunodeficiency virus infection

1 reference

7 January 2021

Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1

1 reference

7 January 2021

Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy

1 reference

7 January 2021

In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity

1 reference

7 January 2021

Dynamics of CCR5 expression by CD4(+) T cells in lymphoid tissues during simian immunodeficiency virus infection

1 reference

7 January 2021

Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection

1 reference

7 January 2021

Regulation of human immunodeficiency virus type 1 infection, beta-chemokine production, and CCR5 expression in CD40L-stimulated macrophages: immune control of viral entry

1 reference

7 January 2021

Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty

1 reference

7 January 2021

Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide

1 reference

7 January 2021

The immune-endocrine loop during aging: role of growth hormone and insulin-like growth factor-I.

1 reference

7 January 2021

Tumor necrosis factor alpha, interleukin 1 and related cytokines in brain development: normal and pathological

1 reference

7 January 2021

Growth hormone, growth factors and hematopoiesis

1 reference

7 January 2021

Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection

1 reference

7 January 2021

Latency and viral persistence in HIV-1 infection

1 reference

7 January 2021

Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus

1 reference

7 January 2021

Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging

1 reference

7 January 2021

Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes

1 reference

7 January 2021

Age-dependent incidence, time course, and consequences of thymic renewal in adults

1 reference

7 January 2021

Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection

1 reference

7 January 2021

Telomerase levels control the lifespan of human T lymphocytes

1 reference

7 January 2021

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

1 reference

7 January 2021

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

1 reference

7 January 2021

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

1 reference

7 January 2021

The flow cytometric analysis of telomere length in antigen-specific CD8+ T cells during acute Epstein-Barr virus infection

1 reference

7 January 2021

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways

1 reference

7 January 2021

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

1 reference

7 January 2021

1 reference

7 January 2021

Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy

1 reference

7 January 2021

Differential Survival of Naive CD4 and CD8 T Cells

1 reference

7 January 2021

Characterization of CD4(+) CTLs ex vivo

1 reference

7 January 2021

Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses

1 reference

7 January 2021

Identifiers

DOI

10.1002/PATH.2276

2 references

Consolidated OpenCitations Corpus – April 2017

2113694

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18161758%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

2113694

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2113694