(Q22253424)

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Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells

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Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells (English)

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insulin receptor

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GOA release 2020-03-11

positive regulation of nitric oxide biosynthetic process

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GOA release 2020-03-11

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author name string

G Zeng

1

author given names

G

author last names

Zeng

1 reference

28 March 2023

F H Nystrom

2

author given names

F H

author last names

Nystrom

1 reference

28 March 2023

L V Ravichandran

3

author given names

L V

author last names

Ravichandran

1 reference

28 March 2023

L N Cong

4

author given names

L N

author last names

Cong

1 reference

28 March 2023

M Kirby

5

author given names

M

author last names

Kirby

1 reference

28 March 2023

H Mostowski

6

author given names

H

author last names

Mostowski

1 reference

28 March 2023

M J Quon

7

author given names

M J

author last names

Quon

1 reference

28 March 2023

language of work or name

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publication date

4 April 2000

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101

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1539-45

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13

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Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Transfection of DNA into isolated rat adipose cells by electroporation: evaluation of promoter activity in transfected adipose cells which are highly responsive to insulin after one day in culture

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

High-efficiency transformation of human endothelial cells by Apo E-mediated transfection with plasmid DNA

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutational analysis of insulin receptor function: consensus and controversy

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives.

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Transfection of human endothelial cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin signalling: metabolic pathways and mechanisms for specificity

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Optimisation of gene transfer into vascular endothelial cells using electroporation

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4.

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Folding of insulin receptor monomers is facilitated by the molecular chaperones calnexin and calreticulin and impaired by rapid dimerization

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficient gene transfer into human umbilical vein endothelial cells allows functional analysis of the human tissue factor gene promoter

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

A generic intron increases gene expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide release accounts for insulin's vascular effects in humans

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

Optimization of transfection of human endothelial cells

1 reference

https://api.crossref.org/works/10.1161%2F01.CIR.101.13.1539

7 January 2021

based on heuristic

inferred from DOI database lookup

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