(Q22253433)

central nervous system development

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

S Singh

1

S

Singh

1 reference

28 March 2023

C M Stellrecht

series ordinal

2

author given names

C M

author last names

Stellrecht

1 reference

28 March 2023

H K Tang

series ordinal

3

author given names

H K

author last names

Tang

1 reference

28 March 2023

G F Saunders

series ordinal

4

author given names

G F

author last names

Saunders

1 reference

28 March 2023

language of work or name

English

0 references

publication date

9 June 2000

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published in

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volume

275

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page(s)

17306-13

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issue

23

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cites work

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Squid Pax-6 and eye development

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Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region

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Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells

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A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells

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Defects of neuronal migration and the pathogenesis of cortical malformations are associated with Small eye (Sey) in the mouse, a point mutation at the Pax-6-locus.

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PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

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Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

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Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6.

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Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing

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A binding site for Pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord

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Direct regulation of rhodopsin 1 by Pax-6/eyeless in Drosophila: evidence for a conserved function in photoreceptors

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DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

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Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding

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Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activity

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Cooperative dimerization of paired class homeo domains on DNA.

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Functional analysis of paired box missense mutations in the PAX6 gene

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DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

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Truncation mutations in the transactivation region of PAX6 result in dominant-negative mutants

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An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity.

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A promoter-associated polymorphic repeat modulates PAX-6 expression in human brain.

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Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3.

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Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue.

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Regulation of PAX-6 gene transcription: alternate promoter usage in human brain.

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High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

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1 reference

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Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations

21 January 2018

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Identification of DNA recognition sequences for the Pax3 paired domain

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Functional PAX-6 gene-linked polymorphic region: potential association with paranoid schizophrenia.

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A binding site for homeodomain and Pax proteins is necessary for L1 cell adhesion molecule gene expression by Pax-6 and bone morphogenetic proteins

21 January 2018

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Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator

21 January 2018

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Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element

21 January 2018

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Developmental appearance of factors that bind specifically to cis-regulatory sequences of a gene expressed in the sea urchin embryo

21 January 2018

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The molecular basis of the undulated/Pax-1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000359200

Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000359200

Genotype/phenotype correlations in aniridia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000359200

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000359200

Characterization of Pax-6 and Hoxa-1 binding to the promoter region of the neural cell adhesion molecule L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000359200

The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein

21 January 2018

1 reference

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Multifunctional lens crystallins and corneal enzymes. More than meets the eye

21 January 2018

1 reference

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Pax genes, mutants and molecular function

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Role of Olf-1 and Pax-6 transcription factors in neurodevelopment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000359200