(Q22254650)

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The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes

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The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes (English)

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Four and a half LIM domains 2

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GOA release 2020-03-11

identical protein binding

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GOA release 2020-03-11

object named as

D Geerts

2

author given names

D

author last names

Geerts

1 reference

8 February 2023

author name string

V Wixler

1

author given names

V

author last names

Wixler

1 reference

8 February 2023

E Laplantine

3

author given names

E

author last names

Laplantine

1 reference

8 February 2023

D Westhoff

4

author given names

D

author last names

Westhoff

1 reference

8 February 2023

N Smyth

5

author given names

N

author last names

Smyth

1 reference

8 February 2023

M Aumailley

6

author given names

M

author last names

Aumailley

1 reference

8 February 2023

A Sonnenberg

7

author given names

A

author last names

Sonnenberg

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8 February 2023

M Paulsson

8

author given names

M

author last names

Paulsson

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8 February 2023

language of work or name

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publication date

27 October 2000

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Journal of Biological Chemistry

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275

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33669-78

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43

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Zyxin: zinc fingers at sites of cell adhesion

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Slim defines a novel family of LIM-proteins expressed in skeletal muscle

1 reference

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7 January 2021

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The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle

1 reference

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based on heuristic

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The fourth member of the FHL family of LIM proteins is expressed exclusively in the testis

1 reference

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7 January 2021

based on heuristic

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Effects of mutations in the cytoplasmic domain of integrin beta(1) to talin binding and cell spreading.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the cysteine-rich intestinal protein, CRIP

1 reference

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7 January 2021

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A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1 reference

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7 January 2021

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The LIM domain is a modular protein-binding interface

1 reference

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7 January 2021

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The LIM domain: a new structural motif found in zinc-finger-like proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

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Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains

1 reference

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7 January 2021

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Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule

1 reference

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7 January 2021

based on heuristic

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LIM domains: multiple roles as adapters and functional modifiers in protein interactions

1 reference

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7 January 2021

based on heuristic

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Molecular cloning and characterization of FHL2, a novel LIM domain protein preferentially expressed in human heart

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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Integrin cytoplasmic domains as connectors to the cell's signal transduction apparatus

1 reference

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Cell adhesion to a population of laminin isoforms isolated from normal renal tissue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

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based on heuristic

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Integrin cytoplasmic interactions and bidirectional transmembrane signalling

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular interactions in cell adhesion complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin signaling and cell growth control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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Focal adhesion assembly

1 reference

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7 January 2021

based on heuristic

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In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits

1 reference

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The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG

1 reference

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7 January 2021

based on heuristic

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CBP-independent activation of CREM and CREB by the LIM-only protein ACT

1 reference

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7 January 2021

based on heuristic

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Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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Structure of the carboxy-terminal LIM domain from the cysteine rich protein CRP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

inferred from DOI database lookup

From Src Homology domains to other signaling modules: proposal of the 'protein recognition code'.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

inferred from DOI database lookup

The LIM/double zinc-finger motif functions as a protein dimerization domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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A conserved sequence motif in the integrin beta3 cytoplasmic domain is required for its specific interaction with beta3-endonexin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of Cysteine- and Glycine-rich Protein CRP2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit

1 reference

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7 January 2021

based on heuristic

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Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin

1 reference

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7 January 2021

based on heuristic

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Interaction of the integrin beta1 cytoplasmic domain with ICAP-1 protein

1 reference

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7 January 2021

based on heuristic

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Divalent Cations Differentially Regulate Integrin αIIbCytoplasmic Tail Binding to β3and to Calcium- and Integrin-binding Protein

1 reference

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7 January 2021

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Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8

1 reference

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Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association

1 reference

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Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptors

1 reference

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Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit

1 reference

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7 January 2021

based on heuristic

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Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein

1 reference

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7 January 2021

based on heuristic

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Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleus

1 reference

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7 January 2021

based on heuristic

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ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin

1 reference

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based on heuristic

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CRP1, a LIM domain protein implicated in muscle differentiation, interacts with alpha-actinin

1 reference

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7 January 2021

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Novel roles for alpha3beta1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytes

1 reference

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7 January 2021

based on heuristic

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A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

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Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis.

1 reference

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based on heuristic

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Integrin alpha 2 cytoplasmic domain deletion effects: loss of adhesive activity parallels ligand-independent recruitment into focal adhesions

1 reference

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based on heuristic

inferred from DOI database lookup

beta1-integrin cytoplasmic subdomains involved in dominant negative function

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

FHL2, a novel tissue-specific coactivator of the androgen receptor

1 reference

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based on heuristic

inferred from DOI database lookup

Development of a structural model for the cytoplasmic domain of an integrin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

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based on heuristic

inferred from DOI database lookup

Integrins and signal transduction pathways: the road taken

1 reference

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1 reference

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based on heuristic

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The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002519200

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based on heuristic

inferred from DOI database lookup

Integrins: emerging paradigms of signal transduction

1 reference

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based on heuristic

inferred from DOI database lookup

Targeting of cytoskeletal linker proteins to focal adhesion complexes is reduced in fibroblasts adhering to laminin-1 when compared to fibronectin

1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M002519200

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release_n3dqsmaoazb2fclw7fmhbheq5m

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