(Q22306024)

PubMed

PubMed publication ID

15926867

Expert Opinion on Investigational Drugs

28 March 2023

language of work or name

English

0 references

publication date

May 2005

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published in

0 references

volume

14

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issue

5

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page(s)

601-618

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cites work

The GABA-ergic system: a locus of benzodiazepine action

1 reference

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Type I and type II GABAA-benzodiazepine receptors produced in transfected cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.14.5.601

The 'ABC' of GABA receptors

20 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.14.5.601

Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

20 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.14.5.601

Emotion circuits in the brain

20 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.14.5.601

Anxioselective compounds acting at the GABA(A) receptor benzodiazepine binding site

20 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.14.5.601

Pharmacokinetic and pharmacodynamic interactions of bretazenil and diazepam with alcohol

20 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.14.5.601

The road to tranquility: the search for selective anti-anxiety agents

20 April 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Use of benzodiazepines in anxiety disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Current benzodiazepine issues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Cognitive and sedative effects of benzodiazepine use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Benzodiazepines and risk of hip fractures in older people: a review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Relative Abuse Liability of Different Benzodiazepines in

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Consequences of the 1989 New York State Triplicate Benzodiazepine Prescription Regulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Properties of 3H-diazepam binding to benzodiazepine receptors in rat cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

The Benzodiazepine Receptor in Normal and Pathological Human Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Resolution of two biochemically and pharmacologically distinct benzodiazepine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Some properties of brain specific benzodiazepine receptors: New evidence for multiple receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

3HPropyl ?-Carboline-3-Carboxylate as a Selective Radioligand for the BZ1Benzodiazepine Receptor Subclass

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Affinity of various ligands for benzodiazepine receptors in rat cerebellum and hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Structural and functional basis for GABAA receptor heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Anxiety over GABA(A) receptor structure relieved by AChBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Analysis of the set of GABA(A) receptor genes in the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Subunit composition, distribution and function of GABA(A) receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Techniques: Use of concatenated subunits for the study of ligand-gated ion channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Gamma-aminobutyric acidA receptor alpha 5-subunit creates novel type II benzodiazepine receptor pharmacology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Cloning, pharmacological characteristics and expression pattern of the rat GABAA receptor alpha 4 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Pharmacology of recombinant gamma-aminobutyric acidA receptors rendered diazepam-insensitive by point-mutated alpha-subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

A review of neuropeptide and neuroendocrine dysregulation in anorexia and bulimia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Sleep EEG changes after zolpidem in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Molecular and neuronal substrate for the selective attenuation of anxiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Diazepam-induced changes in sleep: role of the alpha 1 GABA(A) receptor subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Diazepam-induced changes on sleep and the EEG spectrum in mice: role of the alpha3-GABA(A) receptor subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Selective, orally active gamma-aminobutyric acidA alpha5 receptor inverse agonists as cognition enhancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Anxiogenic properties of an inverse agonist selective for alpha3 subunit-containing GABA A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Novel anxiolytics that act as partial agonists at benzodiazepine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Benzodiazepines on trial: a research strategy for their rehabilitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

From GABAA receptor diversity emerges a unified vision of GABAergic inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Molecular actions of (S)-desmethylzopiclone (SEP-174559), an anxiolytic metabolite of zopiclone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Toxicokinetics in drug development: an overview of toxicokinetic application in the development of PNU-101017, an anxiolytic drug candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Induction of a hepatic toxic syndrome in the Dutch-belted rabbit by a quinoxalinone anxiolytic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Antipsychotic effects of bretazenil, a partial benzodiazepine agonist in acute schizophrenia--a study group report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

A double-blind, placebo-controlled trial of abecarnil and diazepam in the treatment of patients with generalized anxiety disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

[3H]L-655,708, a novel ligand selective for the benzodiazepine site of GABAA receptors which contain the alpha 5 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

3-Heteroaryl-2-pyridones: benzodiazepine site ligands with functional delectivity for alpha 2/alpha 3-subtypes of human GABA(A) receptor-ion channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

6,7-Dihydro-2-benzothiophen-4(5H)-ones: a novel class of GABA-A alpha5 receptor inverse agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Identification of a Novel, Selective GABAAα5 Receptor Inverse Agonist Which Enhances Cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

3,4-Dihydronaphthalen-1(2H)-ones: novel ligands for the benzodiazepine site of alpha5-containing GABAA receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Modifying quinolone antibiotics yields new anxiolytics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Different GABAA receptor subtypes mediate the anxiolytic, abuse-related, and motor effects of benzodiazepine-like drugs in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

Randomized, double-blind, placebo-controlled trial of the efficacy and tolerability of a new isoindoline derivative (DN-2327) in generalized anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

7 January 2021

Stereoselective discriminative stimulus effects of zopiclone in rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

7 January 2021

SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

7 January 2021

Molecular targets for the myorelaxant action of diazepam.

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

7 January 2021

Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux.

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

7 January 2021

Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor.

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

7 January 2021

https://api.crossref.org/works/10.1517%2F13543784.14.5.601

1 reference

7 January 2021