Wikidata

(Q22676641)

English

H4 clustered histone 13

mammalian protein found in Homo sapiens

  • HIST1H4L
  • H4C4
  • HIST1H4A
  • histone cluster 1, H4j
  • H4 histone family, member K
  • HIST1H4F
  • histone 1, H4l
  • histone cluster 1, H4k
  • HIST1H4C
  • histone cluster 1, H4d
  • H4 histone family, member D
  • histone cluster 1, H4l
  • HIST1H4I
  • histone H4
  • histone 1, H4e
  • H4C15
  • histone cluster 1 H4 family member d
  • HIST1H4H
  • histone cluster 1, H4e
  • histone 1, H4d
  • H4 histone family, member B
  • histone 2, H4b
  • histone cluster 1 H4 family member l
  • histone 1, H4j
  • HIST1H4K
  • H4 histone family, member E
  • HIST2H4A
  • HIST1H4B
  • HIST1H4E
  • HIST1H4D
  • H4C13
  • HIST4H4
  • HIST1H4J
  • histone cluster 2 H4 family member b
  • HIST2H4B
  • histone cluster 2, H4b
  • histone 1, H4k
  • H4 histone family, member J
In more languages

Statements

molecular function
protein binding
determination method
IPI
58 references
retrieved
8 April 2019
stated in
PR-Set7 establishes a repressive trans-tail histone code that regulates differentiation
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Human PIH1 associates with histone H4 to mediate the glucose-dependent enhancement of pre-rRNA synthesis
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
L3MBTL1, a histone-methylation-dependent chromatin lock
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Identification of HiNF-P, a Key Activator of Cell Cycle-Controlled Histone H4 Genes at the Onset of S Phase
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Molecular functions of the TLE tetramerization domain in Wnt target gene repression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The CH2 domain of CBP/p300 is a novel zinc finger
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The molecular basis for histone H4- and H2A-specific amino-terminal acetylation by NatD
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of the human HP1 interactome reveals novel binding partners
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Three proteins define a class of human histone deacetylases related to yeast Hda1p
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Crystal structure of the human centromeric nucleosome containing CENP-A
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Crystal structure of the human PRMT5:MEP50 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
An acetyl-methyl switch drives a conformational change in p53.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of interaction partners of H4 histone by a new proteomics approach
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Coactivator CBP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
L3MBTL1, a histone-methylation-dependent chromatin lock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Quantitative reactivity profiling predicts functional cysteines in proteomes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the variant histone H3.3–H4 heterodimer in complex with its chaperone DAXX
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Specificity and mechanism of the histone methyltransferase Pr-Set7.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Tudor, MBT and chromo domains gauge the degree of lysine methylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
retrieved
8 April 2019
stated in
New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62805
determination method
IPI
cell component
biological process
nucleosome assembly
determination method
IBA
IDA
IEA
6 references
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62805&geneProductId=UniProtKB:P62805
determination method
IEA
retrieved
1 January 2018
stated in
Structure of human nucleosome containing the testis-specific histone variant TSH2B
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62805&geneProductId=UniProtKB:P62805
determination method
IDA
retrieved
1 January 2018
stated in
Human tNASP promotes in vitro nucleosome assembly with histone H3.3
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62805&geneProductId=UniProtKB:P62805
determination method
IDA
retrieved
1 January 2018
stated in
Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62805&geneProductId=UniProtKB:P62805
determination method
IDA
retrieved
1 January 2018
stated in
Structures of human nucleosomes containing major histone H3 variants
GOA
curator
UniProt
UniProt protein ID
P62805
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62805&geneProductId=UniProtKB:P62805
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62805&geneProductId=UniProtKB:P62805
determination method
IBA

Identifiers

UniProt protein ID
P62805
0 references
Ensembl protein ID
ENSP00000480960
0 references
ENSP00000481486
0 references
ENSP00000366974
0 references
ENSP00000481343
0 references
ENSP00000478786
0 references
ENSP00000478519
0 references
ENSP00000462667
0 references
ENSP00000244537
0 references
ENSP00000484789
0 references
PDB structure ID
 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q22676641&oldid=2023043092"