(Q27644297)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26912361%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5 (English)

1 reference

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8 March 2020

4

1 reference

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8 March 2020

author name string

Konstantinos J Mavrakis

1

1 reference

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8 March 2020

E Robert McDonald

2

1 reference

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8 March 2020

Michael R Schlabach

3

1 reference

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8 March 2020

Gregory R Hoffman

5

1 reference

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8 March 2020

Antoine deWeck

6

1 reference

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8 March 2020

David A Ruddy

7

1 reference

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8 March 2020

Kavitha Venkatesan

8

1 reference

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8 March 2020

Jianjun Yu

9

1 reference

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8 March 2020

Gregg McAllister

10

1 reference

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8 March 2020

Mark Stump

11

1 reference

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8 March 2020

Rosalie deBeaumont

12

1 reference

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8 March 2020

Samuel Ho

13

1 reference

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8 March 2020

Yingzi Yue

14

1 reference

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8 March 2020

Yue Liu

15

1 reference

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8 March 2020

Yan Yan-Neale

16

1 reference

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8 March 2020

Guizhi Yang

17

1 reference

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8 March 2020

Fallon Lin

18

1 reference

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8 March 2020

Hong Yin

19

1 reference

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8 March 2020

Hui Gao

20

1 reference

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8 March 2020

D Randal Kipp

21

1 reference

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8 March 2020

Songping Zhao

22

1 reference

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8 March 2020

Joshua T McNamara

23

1 reference

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8 March 2020

Elizabeth R Sprague

24

1 reference

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8 March 2020

Bing Zheng

25

1 reference

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8 March 2020

Ying Lin

26

1 reference

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8 March 2020

Young Shin Cho

27

1 reference

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8 March 2020

Justin Gu

28

1 reference

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8 March 2020

Kenneth Crawford

29

1 reference

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8 March 2020

David Ciccone

30

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8 March 2020

Alberto C Vitari

31

1 reference

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8 March 2020

Albert Lai

32

1 reference

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8 March 2020

Vladimir Capka

33

1 reference

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8 March 2020

Kristen Hurov

34

1 reference

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8 March 2020

Jeffery A Porter

35

1 reference

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8 March 2020

John Tallarico

36

1 reference

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8 March 2020

Craig Mickanin

37

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8 March 2020

Emma Lees

38

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8 March 2020

Raymond Pagliarini

39

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8 March 2020

Nicholas Keen

40

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8 March 2020

Tobias Schmelzle

41

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8 March 2020

Francesco Hofmann

42

1 reference

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8 March 2020

Frank Stegmeier

43

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8 March 2020

William R Sellers

44

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8 March 2020

language of work or name

English

0 references

publication date

11 February 2016

1 reference

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8 March 2020

1 reference

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8 March 2020

volume

351

1 reference

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8 March 2020

page(s)

1208-1213

1 reference

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8 March 2020

issue

6278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26912361%20AND%20SRC:MED&resulttype=core&format=json

Crystal structure of the human PRMT5:MEP50 complex

8 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAD5944

Passenger deletions generate therapeutic vulnerabilities in cancer

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAD5944

Methylthioadenosine Phosphorylase Regulates Ornithine Decarboxylase by Production of Downstream Metabolites

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAD5944

Data processing and analysis with the autoPROC toolbox

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAD5944

Overview of the CCP4 suite and current developments

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAD5944

Features and development of Coot

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAD5944

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

An introduction to data reduction: space-group determination, scaling and intensity statistics

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Genetic screens in human cells using the CRISPR-Cas9 system

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Vesicular stomatitis viruses resistant to the methylase inhibitor sinefungin upregulate RNA synthesis and reveal mutations that affect mRNA cap methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

PRMT5 (Janus Kinase-binding Protein 1) Catalyzes the Formation of Symmetric Dimethylarginine Residues in Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Deregulation of protein methylation in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Methylthioadenosine toxicity and metabolism to methionine in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Tumorigenic activity and therapeutic inhibition of Rheb GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

Enzyme-dependent lysine deprotonation in EZH2 catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

How good are my data and what is the resolution?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD5944

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAD5944

2 references

Consolidated OpenCitations Corpus – April 2017

1619625

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26912361%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1619625

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

1619625