(Q27700259)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25915199%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models (English)

1 reference

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6 March 2020

30

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6 March 2020

author name string

Elayne Chan-Penebre

1

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6 March 2020

Kristy G Kuplast

2

1 reference

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6 March 2020

Christina R Majer

3

1 reference

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6 March 2020

P Ann Boriack-Sjodin

4

1 reference

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6 March 2020

Tim J Wigle

5

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6 March 2020

L Danielle Johnston

6

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6 March 2020

Nathalie Rioux

7

1 reference

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6 March 2020

Michael J Munchhof

8

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6 March 2020

Lei Jin

9

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6 March 2020

Suzanne L Jacques

10

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6 March 2020

Kip A West

11

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6 March 2020

Trupti Lingaraj

12

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6 March 2020

Kimberly Stickland

13

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6 March 2020

Scott A Ribich

14

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6 March 2020

Alejandra Raimondi

15

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6 March 2020

Margaret Porter Scott

16

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6 March 2020

Nigel J Waters

17

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6 March 2020

Roy M Pollock

18

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6 March 2020

Jesse J Smith

19

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6 March 2020

Olena Barbash

20

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6 March 2020

Melissa Pappalardi

21

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6 March 2020

Thau F Ho

22

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6 March 2020

Khyati P Oza

24

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6 March 2020

Kathleen T Gallagher

25

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6 March 2020

Ryan Kruger

26

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6 March 2020

Mikel P Moyer

27

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6 March 2020

Robert A Copeland

28

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6 March 2020

Richard Chesworth

29

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6 March 2020

Kelvin Nurse

23

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6 March 2020

publication date

27 April 2015

1 reference

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6 March 2020

published in

Nature Chemical Biology

1 reference

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6 March 2020

volume

11

1 reference

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6 March 2020

page(s)

432-437

1 reference

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6 March 2020

issue

6

1 reference

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Arginine methylation controls growth regulation by E2F-1

6 March 2020

cites work

1 reference

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Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

20 April 2017

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The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity

20 April 2017

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Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins

20 April 2017

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The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins

20 April 2017

1 reference

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Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln

20 April 2017

1 reference

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Crystal structure of the human PRMT5:MEP50 complex

20 April 2017

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Structural insights into protein arginine symmetric dimethylation by PRMT5

20 April 2017

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Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase

20 April 2017

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Biomimetic catalysis of SN2 reactions through cation-.pi. interactions. The role of polarizability in catalysis

20 April 2017

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20 April 2017

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

20 April 2017

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Overview of the CCP4 suite and current developments

20 April 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 April 2017

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Features and development of Coot

20 April 2017

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New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

20 April 2017

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How good are my data and what is the resolution?

20 April 2017

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Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.

20 April 2017

1 reference

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Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1810

Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1810

Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade

21 January 2018

1 reference

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Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4.

21 January 2018

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Versatility of PRMT5-induced methylation in growth control and development.

21 January 2018

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The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans

21 January 2018

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A proteomic analysis of arginine-methylated protein complexes

21 January 2018

1 reference

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Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs

21 January 2018

1 reference

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Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1810

Small molecule regulators of protein arginine methyltransferases

21 January 2018

1 reference

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Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1.

21 January 2018

1 reference

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Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1).

21 January 2018

1 reference

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Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1).

21 January 2018

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1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).

21 January 2018

1 reference

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Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies.

21 January 2018

1 reference

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Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors

21 January 2018

1 reference

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A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation

21 January 2018

1 reference

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Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1810

Substrate specificity, processivity, and kinetic mechanism of protein arginine methyltransferase 5.

21 January 2018

1 reference

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21 January 2018

The cation-π interaction

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1810

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1810

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

21 January 2018

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Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma

21 January 2018

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Analyzing a kinetic titration series using affinity biosensors

21 January 2018

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PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145

21 January 2018

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12 December 2020

A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)

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12 December 2020

The titerless infected-cells preservation and scale-up (TIPS) method for large-scale production of NO-sensitive human soluble guanylate cyclase (sGC) from insect cells infected with recombinant baculovirus

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12 December 2020

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

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12 December 2020

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

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12 December 2020

A simple assay for detection of small-molecule redox activity

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12 December 2020

Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation

1 reference

12 December 2020

Discovery of a Dual PRMT5-PRMT7 Inhibitor

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1810

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEMBIO.1810

2 references

Consolidated OpenCitations Corpus – April 2017

686689

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25915199%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 March 2020

1025878256

0 references

686689

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

686689