(Q22679008)

English

Cathepsin K

mammalian protein found in Homo sapiens

cathepsin X
cathepsin K
cathepsin O2
CTSK
cathepsin O
cathepsin O1

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

fibronectin binding

determination method

1 reference

26 September 2017

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

cysteine-type peptidase activity

determination method

3 references

26 September 2017

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

collagen binding

determination method

1 reference

26 September 2017

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

peptidase activity

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

protein binding

determination method

1 reference

26 September 2017

Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

hydrolase activity

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

proteoglycan binding

determination method

1 reference

26 September 2017

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

serine-type endopeptidase activity

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

extracellular region

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

endolysosome lumen

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

determination method

determination method

1 reference

26 September 2017

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

intracellular membrane-bounded organelle

determination method

1 reference

26 September 2017

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

lysosomal lumen

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

biological process

intramembranous ossification

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

positive regulation of protein targeting to mitochondrion

determination method

1 reference

26 September 2017

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

extracellular matrix disassembly

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

bone resorption

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

determination method

3 references

26 September 2017

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

toll-like receptor signaling pathway

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

regulation of autophagy of mitochondrion

determination method

1 reference

26 September 2017

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

proteolysis involved in cellular protein catabolic process

determination method

1 reference

26 September 2017

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

regulation of keratinocyte differentiation

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43235&geneProductId=UniProtKB:P43235

determination method

physically interacts with

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL481611

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL371064

Identifiers

MeSH descriptor ID

subject named as

Cathepsin K

0 references

D08.811.277.656.224.405

0 references

D08.811.277.656.262.500.156

0 references

D08.811.277.656.300.200.156

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000271651

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000271651

ENSP00000405083

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000405083

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q22679008&oldid=2023044553"