(Q23911183)

9 August 2017

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title

Molecular mechanisms of arsenic carcinogenesis (English)

2 references

12 July 2017

NIOSH Health Effects Laboratory Division

9 August 2017

object named as

HELD

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25 September 2023

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19 July 2017

29 March 2020

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29 March 2020

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29 March 2020

4

Xianglin Shi

Xianglin

Shi

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9 August 2017

Chuanshu Huang

1

Chuanshu

Huang

1 reference

9 August 2017

Qingdong Ke

series ordinal

2

author given names

Qingdong

author last names

Ke

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9 August 2017

Max Costa

series ordinal

3

author given names

Max

author last names

Costa

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9 August 2017

language of work or name

English

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inferred from title

process of elimination

publication date

January 2004

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1 January 2004

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Molecular and Cellular Biochemistry

9 August 2017

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9 August 2017

255

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9 August 2017

57-66

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9 August 2017

1/2

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1-2

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on focus list of Wikimedia project

9 August 2017

Wikimedia–NIOSH collaboration

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1 reference

2 February 2024

Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis.

1 reference

12 December 2020

Arsenic contamination in groundwater in six districts of West Bengal, India: the biggest arsenic calamity in the world

1 reference

12 December 2020

Induction of chromatid breaks and tetraploidy in Chinese hamster ovary cells by treatment with sodium arsenite during the G2 phase

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12 December 2020

Risk of internal cancers from arsenic in drinking water

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12 December 2020

Arsenite, but not cadmium, induces ornithine decarboxylase and heme oxygenase activity in rat liver: relevance to arsenic carcinogenesis.

1 reference

12 December 2020

Role of quinoids in estrogen carcinogenesis.

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12 December 2020

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

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12 December 2020

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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12 December 2020

Function and activation of NF-kappa B in the immune system

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12 December 2020

Identification and classification of p53-regulated genes

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12 December 2020

What are the chemical forms of arsenic in urine, and what can they tell us about exposure?

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12 December 2020

Experimental models and biological mechanisms for tumor promotion.

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12 December 2020

Physiological and toxicological changes in the skin resulting from the action and interaction of metal ions

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12 December 2020

Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-x(L)

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12 December 2020

Arsenic induces oxidant stress and NF-KB activation in cultured aortic endothelial cells

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12 December 2020

Arsenic uptake and metabolism by liver cells is dependent on arsenic oxidation state

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12 December 2020

Preliminary experimental study on carcinogenicity of arsenic trioxide in rat lung

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12 December 2020

The absorption of arsenic and its relation to carcinoma

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12 December 2020

The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

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12 December 2020

Malignant neoplasms among residents who drank well water contaminated by arsenic from a king's yellow factory

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12 December 2020

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12 December 2020

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

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12 December 2020

Arsenic toxicity and potential mechanisms of action

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12 December 2020

As2O3 induces apoptosis of the human B lymphoma cell line MBC-1.

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12 December 2020

Arsenic poisoning in West Bengal

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12 December 2020

In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

1 reference

12 December 2020

Arsenic-induced oxidative stress and its reversibility following combined administration of N-acetylcysteine and meso 2,3-dimercaptosuccinic acid in rats

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12 December 2020

Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity

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12 December 2020

Cytokine modulation of keratinocyte cytokines

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12 December 2020

Differential effects of arsenic(III) and chromium(VI) on nuclear transcription factor binding

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12 December 2020

Metabolism of arsenobetaine in mice, rats and rabbits

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12 December 2020

Oxidative stress and cell cycle checkpoint function.

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12 December 2020

Induction of p53 protein expression by sodium arsenite

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12 December 2020

Granulocyte-macrophage colony stimulating factor gene expression and function during tumor promotion

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12 December 2020

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

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12 December 2020

Monomethylarsonous acid (MMA(III)) is more toxic than arsenite in Chang human hepatocytes

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12 December 2020

GADD45 induction of a G2/M cell cycle checkpoint

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12 December 2020

Arsenic-induced NFkB transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells

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12 December 2020

Activation of PKC is required for arsenite-induced signal transduction

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12 December 2020

DNA damage-inducible transcripts in mammalian cells

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12 December 2020

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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12 December 2020

Carcinomas of the respiratory tract in hamsters given arsenic trioxide and/or benzo[a]pyrene by the pulmonary route

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12 December 2020

Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species

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12 December 2020

Arsenite inhibits two steps in the ubiquitin-dependent proteolytic pathway

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12 December 2020

Genetic control of carcinogenesis in experimental animals

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12 December 2020

c-Src-dependent Activation of the Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase Pathway by Arsenic

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12 December 2020

Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells

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12 December 2020

Mechanisms of arsenic carcinogenicity: genetic or epigenetic mechanisms?

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12 December 2020

Enzymatic methylation of arsenic compounds: IV. In vitro and in vivo deficiency of the methylation of arsenite and monomethylarsonic acid in the guinea pig.

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12 December 2020

Arsenic toxicity is enzyme specific and its affects on ligation are not caused by the direct inhibition of DNA repair enzymes

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12 December 2020

Arsenite retards DNA break rejoining by inhibiting DNA ligation

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12 December 2020

Molecular mechanisms of transformation of C3H/10T1/2 C1 8 mouse embryo cells and diploid human fibroblasts by carcinogenic metal compounds

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12 December 2020

Metabolism of inorganic arsenic (74As) in humans following oral ingestion

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12 December 2020

Clinically relevant findings

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12 December 2020

The consequences of chronic arsenic poisoning among Moselle wine growers. Pathoanatomical investigations of post-mortem examinations performed between 1960 and 1977.

1 reference

12 December 2020

Acquisition of apoptotic resistance in arsenic-induced malignant transformation: role of the JNK signal transduction pathway

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12 December 2020

Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response.

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12 December 2020

Induction of gene amplification by arsenic

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12 December 2020

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

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12 December 2020

Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells.

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12 December 2020

Arsenite stimulates plasma membrane NADPH oxidase in vascular endothelial cells

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12 December 2020

Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity

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12 December 2020

India's spreading health crisis draws global arsenic experts

1 reference

12 December 2020

Comparison of the urinary excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethylarsonate, or dimethylarsinate in man

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12 December 2020

Ecological correlation between arsenic level in well water and age-adjusted mortality from malignant neoplasms.

1 reference

12 December 2020

Reactions of arsenic(III) and arsenic(V) species with glutathione

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12 December 2020

Active oxygen species are involved in the induction of micronuclei by arsenite in XRS-5 cells

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12 December 2020

Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase.

1 reference

12 December 2020

The NF-kappa B and I kappa B proteins: new discoveries and insights

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12 December 2020

MAPKs: new JNK expands the group

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12 December 2020

Mechanisms of arsenic-induced cell transformation

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12 December 2020

Phenylarsine oxide blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, and induces apoptosis of acute myelogenous leukemia cells

1 reference

12 December 2020

Tumor incidence in a chemical carcinogenesis study of nonhuman primates.

1 reference

12 December 2020

Arsenic exposure: health effects and the risk of cancer.

1 reference

12 December 2020

The decomposition of peroxynitrite to nitroxyl anion (NO-) and singlet oxygen in aqueous solution

1 reference

12 December 2020

Arsenic-induced DNA-strand breaks associated with DNA-protein crosslinks in human fetal lung fibroblasts.

1 reference

12 December 2020

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

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12 December 2020

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

12 December 2020

Successful treatment with arsenic trioxide of a patient with ATRA-resistant relapse of acute promyelocytic leukemia

1 reference

12 December 2020

Cutaneous manifestations of chronic arsenicism: review of seventeen cases

1 reference

12 December 2020

Stress proteins induced by arsenic.

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12 December 2020

Ingested arsenic and internal cancer: a historical cohort study followed for 33 years

1 reference

12 December 2020

Effects of exposure protocols on induction of kinetochore-plus and -minus micronuclei by arsenite in diploid human fibroblasts

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12 December 2020

The NF-kappa B activation pathway: its regulation and role in inflammation and cell survival

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12 December 2020

Sodium arsenate induces overproduction of interleukin-1alpha in murine keratinocytes: role of mitochondria

1 reference

12 December 2020

Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway.

1 reference

12 December 2020

Autoradiographic studies on the distribution of arsenic in mice and hamsters administered 74As-arsenite or -arsenate

1 reference

12 December 2020

Comutagenesis of sodium arsenite with ultraviolet radiation in Chinese hamster V79 cells

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12 December 2020

The enigma of arsenic carcinogenesis: role of metabolism

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12 December 2020

Metals and disorders of cell accumulation: modulation of apoptosis and cell proliferation

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12 December 2020

Metal carcinogenesis: mechanistic implications

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12 December 2020

Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

1 reference

12 December 2020

Incidence of internal cancers and ingested inorganic arsenic: a seven-year follow-up study in Taiwan.

1 reference

12 December 2020

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

12 December 2020

Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite

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12 December 2020

Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water

1 reference

12 December 2020

Pathologic changes in rats and dogs from two-year feeding of sodium arsenite or sodium arsenate

1 reference

12 December 2020

Regulation of the thyroid NADPH-dependent H2O2 generator by Ca2+: studies with phenylarsine oxide in thyroid plasma membrane

1 reference

12 December 2020

Sister-chromatid exchange (SCE) among individuals chronically exposed to arsenic in drinking water

1 reference

12 December 2020

Opposite effect of NF-kB and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite

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12 December 2020

Absence of arsenite mutagenicity in E coli and Chinese hamster cells.

1 reference

12 December 2020

The use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia

1 reference

12 December 2020

Cellular uptake and metabolic reduction of pentavalent to trivalent arsenic as determinants of cytotoxicity and morphological transformation

1 reference

12 December 2020

Study on the carcinogenicity of lead arsenate and sodium arsenate and on the possible synergistic effect of diethylnitrosamine.

1 reference

12 December 2020

Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression

1 reference

12 December 2020

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1 reference

12 December 2020

Mechanism of comutagenesis of sodium arsenite with n-methyl-n-nitrosourea

1 reference

12 December 2020

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is expressed in mouse skin in response to tumor-promoting agents and modulates dermal inflammation and epidermal dark cell numbers.

1 reference

12 December 2020

BRCA1 activation of the GADD45 promoter.

1 reference

12 December 2020

Cell and molecular mechanisms of pathogenesis and treatment of cancer

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12 December 2020

Arsenic ingestion and internal cancers: a review

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12 December 2020

Arsenic in drinking water and bladder cancer

1 reference

12 December 2020

Sodium arsenite enhances AP-1 and NFkappaB DNA binding and induces stress protein expression in precision-cut rat lung slices.

1 reference

12 December 2020

Arsenic induces overexpression of growth factors in human keratinocytes

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12 December 2020

Sodium arsenite disturbs mitosis and induces chromosome loss in human fibroblasts

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12 December 2020

Progressive elevation of ap-1 activity during preneoplastic-to-neoplastic progression as modeled in mouse jb6 cell variants

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12 December 2020

Long-term cultured adult human keratinocytes secrete granulocyte-macrophage colony-stimulating factor but not interleukin-3 after cytokine exposure in vitro.

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12 December 2020

Inhibition of AP-1 and NF-kappaB by manganese-containing superoxide dismutase in human breast cancer cells.

1 reference

12 December 2020

Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture.

1 reference

12 December 2020

Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species

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12 December 2020

Biotransformation of dimethylarsinic acid in mouse, hamster and man

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12 December 2020

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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12 December 2020

Antioxidant and redox regulation of gene transcription

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12 December 2020

Predisposing factors in occupational lung cancer: inorganic minerals and chromium

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12 December 2020

Inhibition of DNA ligase activity by arsenite: a possible mechanism of its comutagenesis

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12 December 2020

Requirement of Erk, but not JNK, for arsenite-induced cell transformation

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12 December 2020

DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells

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12 December 2020

Drinking water and cancer

1 reference

12 December 2020

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients

1 reference

12 December 2020

Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites

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12 December 2020

The enzyme inhibitory form of inorganic arsenic

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12 December 2020

NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells

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12 December 2020

An essential role for free radicals and derived species in signal transduction.

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12 December 2020

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

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12 December 2020

Arsenic disrupts cellular levels of p53 and mdm2: a potential mechanism of carcinogenesis

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12 December 2020

Skin cancer and inorganic arsenic: uncertainty-status of risk.

1 reference

12 December 2020

Role of quinones in toxicology.

1 reference

12 December 2020

Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation

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12 December 2020

Chronic arsenic toxicity in west Bengal--the worst calamity in the world.

1 reference

12 December 2020

Effects of sodium arsenite on the survival of UV-irradiated Escherichia Coli: INHIBITION OF A rec A-Dependent function

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12 December 2020

Signal transduction pathways regulated by arsenate and arsenite

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12 December 2020

Concentration and chemical species of arsenic in human tissue

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12 December 2020

Mechanisms and genes of cellular suicide

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12 December 2020

The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase

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12 December 2020

Arsenic enhancement of skin neoplasia by chronic stimulation of growth factors

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12 December 2020

Prevalence of skin cancer in an endemic area of chronic arsenicism in Taiwan

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12 December 2020

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

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12 December 2020

Inorganic arsenic: a need and an opportunity to improve risk assessment

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12 December 2020

Effects of arsenite on p53, p21 and cyclin D expression in normal human fibroblasts -- a possible mechanism for arsenite's comutagenicity

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12 December 2020

Arsenite is a cocarcinogen with solar ultraviolet radiation for mouse skin: an animal model for arsenic carcinogenesis.

1 reference

12 December 2020

Case-control study of bladder cancer and arsenic in drinking water.

1 reference

12 December 2020

Transactivation of AP-1 in AP-1-luciferase reporter transgenic mice by arsenite and arsenate.

1 reference

12 December 2020

A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines

1 reference

12 December 2020

10.1023/B:MCBI.0000007261.04684.78

Identifiers

DOI

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Dimensions Publication ID

9 August 2017

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