(Q23916231)

English

In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily

journal article published in 2004

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scholarly article

1 reference

19 July 2017

In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily (English)

1 reference

12 July 2017

National Institute for Occupational Safety and Health

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1 reference

29 March 2020

author name string

K. A. Usmani

1

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language of work or name

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publication date

1 March 2004

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Drug Metabolism and Disposition

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32

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3

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333-339

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performing organization

East Carolina University

object named as

East Carolina University

1 reference

2 February 2024

on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

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cooperative agreement

1 reference

25 September 2023

Stereoselective sulfoxidation of the pesticide methiocarb by flavin-containing monooxygenase and cytochrome P450-dependent monooxygenases of rat liver microsomes. Anticholinesterase activity of the two sulfoxide enantiomers.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of flavin-containing monooxygenase 5 (FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

A convenient method to discriminate between cytochrome P450 enzymes and flavin-containing monooxygenases in human liver microsomes

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Sulfoxidation of thioether-containing pesticides by the flavin-adenine dinucleotide- dependent monooxygenase of pig liver microsomes.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

The molecular biology of the flavin-containing monooxygenases of man

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Ticlopidine inhibition of phenytoin metabolism mediated by potent inhibition of CYP2C19

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An Approach Using Designed Tienilic Acid Derivatives and Molecular Modeling

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An NMR Study†

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of the Substrate Specificities of Human Liver Cytochrome P450s 2C9 and 2C18: Application to the Design of a Specific Substrate of CYP 2C18

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical relevance of genetic polymorphisms in the human CYP2C subfamily

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 5

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Torsemide metabolism by CYP2C9 variants and other human CYP2C subfamily enzymes

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential developmental and tissue-specific regulation of expression of the genes encoding three members of the flavin-containing monooxygenase family of man, FMO1, FMO3 and FM04

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Flavin adenine dinucleotide--dependent monooxygenase: its role in the sulfoxidation of pesticides in mammals.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.32.3.333

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1124/DMD.32.3.333

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