(Q23916367)

English

Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha1

journal article published in 2006

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scholarly article

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15 October 2024

Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha1 (English)

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12 July 2017

NIOSH Health Effects Laboratory Division

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HELD

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25 September 2023

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2 references

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inferred from title

29 March 2020

neurological disorder

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29 March 2020

toxic encephalopathy

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based on heuristic

inferred from title

Krishnan Sriram

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K. Sriram

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publication date

1 April 2006

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20

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6

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670-682

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on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

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Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

1 reference

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Minocycline enhances MPTP toxicity to dopaminergic neurons

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Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for a cytoprotective response

1 reference

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Evidence for the involvement of TNF and NF-?B in hippocampal synaptic plasticity

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Quantitative immunoblots of proteins resolved from brain homogenates: underestimation of specific protein concentration and of treatment effects

1 reference

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Role of TNF-alpha receptors in mice intoxicated with the parkinsonian toxin MPTP.

1 reference

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Electrophysiological and neurochemical correlates of the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in the mouse

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Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity.

1 reference

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Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

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Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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Degeneration of the nigral dopamine neurons after 6-hydroxydopamine injection into the rat striatum

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Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: relationships between monoamine oxidase, MPTP metabolism and neurotoxicity

1 reference

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MPP+ can disrupt the nigrostriatal dopamine system by acting in the terminal area

1 reference

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A direct comparison of GFAP immunocytochemistry and GFAP concentration in various regions of ethanol-fixed rat and mouse brain

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Microglia: a sensor for pathological events in the CNS

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NF-kappa B transcription factor subunits in rat brain: colocalization of p65 and alpha-MSH.

1 reference

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Quantitative aspects of drug and toxicant-induced astrogliosis

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Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse

1 reference

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The neurotoxicant MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) increases glial fibrillary acidic protein and decreases dopamine levels of the mouse striatum: evidence for glial response to injury

1 reference

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Elevated circulating tumor necrosis factor levels in Alzheimer's disease

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Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

1 reference

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MPTP neurotoxicity to cerebellar Purkinje cells in mice

1 reference

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Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease

1 reference

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7 January 2021

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Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

1 reference

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7 January 2021

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Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease.

1 reference

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Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

1 reference

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7 January 2021

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Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

1 reference

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7 January 2021

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Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum

1 reference

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Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

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Interleukine-1beta and interleukine-6 levels in striatum and other brain structures after MPTP treatment: influence of behavioral lateralization

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Tumor necrosis factor-alpha receptor ablation in a chronic MPTP mouse model of Parkinson's disease

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Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice

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Systemic administration of MPTP induces thalamic neuronal degeneration in mice

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Chemically induced neuronal damage and gliosis: enhanced expression of the proinflammatory chemokine, monocyte chemoattractant protein (MCP)-1, without a corresponding increase in proinflammatory cytokines(1).

1 reference

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Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

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Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

1 reference

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Induction of gp130-related Cytokines and Activation of JAK2/STAT3 Pathway in Astrocytes Precedes Up-regulation of Glial Fibrillary Acidic Protein in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Neurodegeneration

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

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1 reference

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7 January 2021

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Diethyldithiocarbamate potentiates the neurotoxicity of in vivo 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of in vitro 1-methyl-4-phenylpyridinium

1 reference

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7 January 2021

based on heuristic

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Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor- alpha

1 reference

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1 reference

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7 January 2021

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1 reference

https://api.crossref.org/works/10.1096%2FFJ.05-5106COM

7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

https://api.crossref.org/works/10.1096%2FFJ.05-5106COM

7 January 2021

based on heuristic

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1096/FJ.05-5106COM

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