(Q23919607)

8 November 2017

title

Up-regulation of expression of translation factors--a novel molecular mechanism for cadmium carcinogenesis (English)

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NIOSH Health Effects Laboratory Division

8 November 2017

sponsor

object named as

HELD

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25 September 2023

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19 July 2017

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19 July 2017

29 March 2020

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29 March 2020

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29 March 2020

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29 March 2020

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29 March 2020

3

Tong-man Ong

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8 November 2017

Pius Joseph

1

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8 November 2017

author name string

Yi-Xiong Lei

series ordinal

2

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8 November 2017

language of work or name

English

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inferred from title

process of elimination

publication date

1 January 2004

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Molecular and Cellular Biochemistry

8 November 2017

published in

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8 November 2017

volume

255

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8 November 2017

issue

1-2

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8 November 2017

page(s)

93-101

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on focus list of Wikimedia project

8 November 2017

Wikimedia–NIOSH collaboration

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cites work

Regulation of metallothionein gene expression by oxidative stress and metal ions

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12 December 2020

Changes in activity and amount of active elongation factor 1 alpha in aging and immortal human fibroblast cultures.

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12 December 2020

Protective elevations of glutathione and metallothionein in cadmium-exposed mesangial cells

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12 December 2020

Cadmium-regulated genes from the nematode Caenorhabditis elegans. Identification and cloning of new cadmium-responsive genes by differential display

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12 December 2020

Antisense inhibition of translation initiation factor 3 reverses its oncogenic potential

1 reference

12 December 2020

The human leucine zipper-containing guanine-nucleotide exchange protein elongation factor-1 delta

1 reference

12 December 2020

Acute cadmium exposure induces stress-related gene expression in wild-type and metallothionein-I/II-null mice

1 reference

12 December 2020

Eukaryotic protein elongation factors

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12 December 2020

Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

1 reference

12 December 2020

Suppressed oxidant-induced apoptosis in cadmium adapted alveolar epithelial cells and its potential involvement in cadmium carcinogenesis.

1 reference

12 December 2020

Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species

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12 December 2020

Cadmium carcinogenesis in review

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12 December 2020

Deregulation of protein synthesis as a mechanism of neoplastic transformation

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12 December 2020

Use of cell transformation systems for carcinogenicity testing and mechanistic studies of carcinogenesis.

1 reference

12 December 2020

Participation of upstream stimulator factor (USF) in cadmium-induction of the mouse metallothionein-I gene

1 reference

12 December 2020

Cadmium-induced expression of immediate early genes in LLC-PK1 cells

1 reference

12 December 2020

Glutathione peroxidase and catalase in liver, kidney, testis and brain regions of rats following cadmium exposure and subsequent withdrawal

1 reference

12 December 2020

Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis

1 reference

12 December 2020

Translational control: the cancer connection

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12 December 2020

Cadmium-induced mRNA expression of Hsp32 is augmented in metallothionein-I and -II knock-out mice

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12 December 2020

Elongation factor-1 alpha gene determines susceptibility to transformation

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12 December 2020

Differential screening of a human pancreatic adenocarcinoma lambda gt11 expression library has identified increased transcription of elongation factor EF-1 alpha in tumour cells

1 reference

12 December 2020

DNA microarray analysis of human gene expression induced by a non-lethal dose of cadmium

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12 December 2020

Expression of an elongation factor 1 gamma-related sequence in adenocarcinomas of the colon

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12 December 2020

Overproduction of ornithine decarboxylase caused by relief of translational repression is associated with neoplastic transformation.

1 reference

12 December 2020

eIF4E expression in tumors: its possible role in progression of malignancies

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12 December 2020

Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

1 reference

12 December 2020

Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis

1 reference

12 December 2020

The proto-oncogene/translation factor eIF4E: A survey of its expression in breast carcinomas

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12 December 2020

Molecular cloning and functional analysis of a novel cadmium-responsive proto-oncogene

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12 December 2020

Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display

1 reference

12 December 2020

Translation initiation factor eIF-4A1 mRNA is consistently overexpressed in human melanoma cells in vitro

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12 December 2020

Metal carcinogenesis: mechanistic implications

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12 December 2020

Activation of the c-myc gene by translocation: a model for translational control

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12 December 2020

Translational infidelity and human cancer: role of the PTI-1 oncogene

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12 December 2020

Role of ATM in oxidative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdCl2.

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12 December 2020

Ras mediates translation initiation factor 4E-induced malignant transformation

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12 December 2020

Elevated levels of eukaryotic translation initiation factor eIF-4E, mRNA in a broad spectrum of transformed cell lines

1 reference

12 December 2020

Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both translational fidelity and the requirement for nucleotide exchange.

1 reference

12 December 2020

Overexpression of an elongation factor-1 gamma-hybridizing RNA in colorectal adenomas.

1 reference

12 December 2020

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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12 December 2020

Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae

1 reference

12 December 2020

The role of eIF4 in cell proliferation

1 reference

12 December 2020

Scientific basis for an occupational standard for cadmium

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12 December 2020

Transforming and carcinogenic potential of cadmium chloride in BALB/c-3T3 cells

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12 December 2020

Translation factors as effectors of cell growth and tumorigenesis

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12 December 2020

Toxicological principles of metal carcinogenesis with special emphasis on cadmium

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12 December 2020

Oncogenic potential of mouse translation elongation factor-1 delta, a novel cadmium-responsive proto-oncogene

1 reference

12 December 2020

Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes

1 reference

12 December 2020

Fruit flies with additional expression of the elongation factor EF-1 alpha live longer

1 reference

12 December 2020

Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor

1 reference

12 December 2020

Enhanced expression of translation factor mRNAs in hepatocellular carcinoma.

1 reference

12 December 2020

Elongation factor-1 alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma

1 reference

12 December 2020

Decreasing the level of translation initiation factor 4E with antisense RNA causes reversal of ras-mediated transformation and tumorigenesis of cloned rat embryo fibroblasts.

1 reference

12 December 2020

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1 reference

12 December 2020

Regulation of translation and cell growth by eIF-4E.

1 reference

12 December 2020

Malignant transformation by overproduction of translation initiation factor eIF4G.

1 reference

12 December 2020

Protein synthesis, cell growth and oncogenesis

1 reference

12 December 2020

Expression of elongation factor-1 gamma-related sequence in human pancreatic cancer

1 reference

12 December 2020

Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms

1 reference

12 December 2020

Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium

1 reference

12 December 2020

10.1023/B:MCBI.0000007265.38475.F7

Identifiers

DOI

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Dimensions Publication ID

8 November 2017

1047382343

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NIOSHTIC-2 ID

20024217

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1 reference