(Q23923854)

English

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2·Keap1·Cul3 complex and recruiting Nrf2·Maf to the antioxidant response element enhancer

journal article published in 2006

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scholarly article

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15 October 2024

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2·Keap1·Cul3 complex and recruiting Nrf2·Maf to the antioxidant response element enhancer (English)

1 reference

12 July 2017

NIOSH Health Effects Laboratory Division

object named as

HELD

1 reference

25 September 2023

1 reference

15 October 2024

1 reference

29 March 2020

1 reference

29 March 2020

4

object named as

Qiang Ma

0 references

object named as

Gary X Lin

3

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author name string

Xiaoqing He

1

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Michael G Chen

2

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language of work or name

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publication date

18 August 2006

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Journal of Biological Chemistry

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281

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33

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23620-23631

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on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

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Arsenic geochemistry and health

1 reference

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Arsenic: health effects, mechanisms of actions, and research issues

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Blackfoot disease and arsenic: a never-ending story.

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Developmental toxicity of inorganic arsenic in whole embryo: culture oxidation state, dose, time, and gestational age dependence

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Developmental and reproductive toxicity of inorganic arsenic: Animal studies and human concerns

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Environmental cardiovascular disease

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The potential of arsenic trioxide in the treatment of malignant disease: past, present, and future

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History of the treatment of psoriasis

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New mechanisms of drug resistance in parasitic protozoa

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Arsenical-resistant trypanosomes lack an unusual adenosine transporter

1 reference

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The role of arsenic-thiol interactions in metalloregulation of the ars operon

1 reference

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Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies

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Methylated trivalent arsenic species are genotoxic

1 reference

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Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)

1 reference

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21 January 2018

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

1 reference

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21 January 2018

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

1 reference

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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1 reference

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21 January 2018

The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

1 reference

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21 January 2018

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

1 reference

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21 January 2018

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

1 reference

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21 January 2018

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

1 reference

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21 January 2018

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

1 reference

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21 January 2018

Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice

1 reference

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21 January 2018

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

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21 January 2018

Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2

1 reference

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21 January 2018

Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage

1 reference

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21 January 2018

2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhR

1 reference

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21 January 2018

Differential induction of quinone reductase by phytoestrogens and protection against oestrogen-induced DNA damage

1 reference

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21 January 2018

Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: A screening assay for anticarcinogenic enzyme inducers

1 reference

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21 January 2018

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway

1 reference

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21 January 2018

Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide

1 reference

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21 January 2018

Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604120200

21 January 2018

Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604120200

21 January 2018

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

1 reference

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21 January 2018

Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1

1 reference

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Carcinogenicity, teratogenicity and mutagenicity of arsenic.

1 reference

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7 January 2021

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10.1074/JBC.M604120200

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