(Q24291740)

GOA release 2020-03-11

Bruton's tyrosine kinase

1 reference

release of sequestered calcium ion into cytosol

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

4

C Palmieri

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author name string

W Liu

1

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I Quinto

2

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X Chen

3

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R L Rabin

5

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O M Schwartz

6

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D L Nelson

7

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G Scala

Role of Bruton's tyrosine kinase in immunodeficiency

8

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language of work or name

English

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publication date

October 2001

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published in

Nature Immunology

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volume

2

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issue

10

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page(s)

939-46

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Mutation analysis of the Bruton's tyrosine kinase gene in X-linked agammaglobulinemia: identification of a mutation which affects the same codon as is altered in immunodeficient xid mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Xid-like phenotypes: a B cell signalosome takes shape

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Impaired expansion of mouse B cell progenitors lacking Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

The G protein G alpha12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Tec homology (TH) adjacent to the PH domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

SHIP modulates immune receptor responses by regulating membrane association of Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Btk function in B cell development and response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Regulatory intramolecular association in a tyrosine kinase of the Tec family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

The SH3 domain of Bruton's tyrosine kinase displays altered ligand binding properties when auto-phosphorylated in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Regulation of Btk function by a major autophosphorylation site within the SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Phosphorylation of two regulatory tyrosine residues in the activation of Bruton's tyrosine kinase via alternative receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Analysis of signaling via surface immunoglobulin receptors on B cells from CBA/N mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

The primary immunodeficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

7 January 2021

A novel mutation (Cys145-->Stop) in Bruton's tyrosine kinase is associated with newly diagnosed X-linked agammaglobulinemia in a 51-year-old male.

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

7 January 2021

Tyrosine phosphorylation of the Wiskott-Aldrich syndrome protein by Lyn and Btk is regulated by CDC42

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

7 January 2021

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

1 reference

https://api.crossref.org/works/10.1038%2FNI1001-939

7 January 2021