(Q24294275)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

main subject

hypoxia

0 references

nitric oxide synthase 1

1 reference

GOA release 2020-03-11

response to hypoxia

1 reference

GOA release 2020-03-11

author

Mourad Toporsian

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Jeremy A. Scott

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Hwee Teoh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Michael E Ward

1

1 reference

ORCID Public Data File 2021

author name string

Vasanthi Govindaraju

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Adrian Quan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Avraham D Wener

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Guilin Wang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Siân C Bevan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Derek C Newton

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Philip A Marsden

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

1 November 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

9 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

3128-3139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

9 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Comparison of the capacity of different viral internal ribosome entry segments to direct translation initiation in poly(A)-dependent reticulocyte lysates

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

An alternative promoter of the human neuronal nitric oxide synthase gene is expressed specifically in Leydig cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Downregulation of endothelial nitric oxide synthase in rat aorta after prolonged hypoxia in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Nitric oxide synthases: roles, tolls, and controls

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Proline hydroxylation and gene expression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Activating transcription factor 4 is translationally regulated by hypoxic stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Neuronal nitric oxide synthase as a novel anti-atherogenic factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Cellular internal ribosome entry segments: structures, trans-acting factors and regulation of gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Single-nucleotide promoter polymorphism alters transcription of neuronal nitric oxide synthase exon 1c in infantile hypertrophic pyloric stenosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Localization of nitric oxide synthase type III in the internal thoracic and radial arteries and the great saphenous vein: a comparative immunohistochemical study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Translational regulation of human neuronal nitric-oxide synthase by an alternatively spliced 5'-untranslated region leader exon

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Complex regulation of human neuronal nitric-oxide synthase exon 1c gene transcription. Essential role of Sp and ZNF family members of transcription factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Regulation of diaphragmatic nitric oxide synthase expression during hypobaric hypoxia.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Role of neuronal nitric oxide synthase in hypoxia-induced anapyrexia in rats

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

RNA diversity has profound effects on the translation of neuronal nitric oxide synthase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Neuronal NOS: gene structure, mRNA diversity, and functional relevance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

C-Myc 5' untranslated region contains an internal ribosome entry segment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Tissue- and development-specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Differential regulation of the two neuronal nitric-oxide synthase gene promoters by the Oct-2 transcription factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Transcription of the human neuronal nitric oxide synthase gene in the central nervous system is mediated by multiple promoters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Two closely linked but separable promoters for human neuronal nitric oxide synthase gene transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Number of CpG islands and genes in human and mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Estrogen selectively up-regulates eNOS and nNOS in reproductive arteries by transcriptional mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Increased nitric oxide production following chronic hypoxia contributes to attenuated systemic vasoconstriction

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Neuronal nitric oxide synthase is expressed in rat vascular smooth muscle cells: activation by angiotensin II in hypertension

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Involvement of nitric oxide in the pathophysiology of acute heat stress in the rat. Influence of a new antioxidant compound H-290/51.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Activation of nitric oxide synthase gene expression by hypoxia in central and peripheral neurons.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester decreases ischemic damage in reversible focal cerebral ischemia in hyperglycemic rats

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Structural organization of the human neuronal nitric oxide synthase gene (NOS1).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Arterial hypoxemia in awake dogs. Role of the sympathetic nervous system in mediating the systemic hemodynamic and regional blood flow responses.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Reflex cardiovascular responses after 36 hr of hypoxia

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Post-transcriptional regulation of endothelial nitric-oxide synthase by an overlapping antisense mRNA transcript

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Exogenous biopterins requirement for iNOS function in vascular smooth muscle cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Caspase-independent cell death by low concentrations of nitric oxide in PC12 cells: involvement of cytochrome C oxidase inhibition and the production of reactive oxygen species in mitochondria

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Nitric oxide synthase induction, cGMP elevation, and biopterin synthesis in vascular smooth muscle cells stimulated with interleukin-1beta in hypoxia

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Hypoxia activates Akt and induces phosphorylation of GSK-3 in PC12 cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Role of nitric oxide in hypoxic hypometabolism in rats.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265848

Induction of neuronal type nitric oxide synthase in skeletal muscle by chronic electrical stimulation in vivo

29 November 2018

1 reference

12 December 2020

Identification of a novel repressive element that contributes to neuron-specific gene expression

1 reference

12 December 2020

Hyporeactivity of rat diaphragmatic arterioles after exposure to hypoxia in vivo. Role of the endothelium

1 reference

12 December 2020

Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels

1 reference

12 December 2020

Potential functional significance of brain-type and muscle-type nitric oxide synthase I expressed in adventitia and media of rat aorta

1 reference

12 December 2020

Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells

1 reference

12 December 2020

In vivo expression profile of an endothelial nitric oxide synthase promoter-reporter transgene

1 reference

12 December 2020

Distinct expression of splice variants of neuronal nitric oxide synthase in the human gastrointestinal tract

1 reference

12 December 2020

Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences

1 reference

12 December 2020

O2 extraction by canine hindlimb during alpha-adrenergic blockade and hypoxic hypoxia

1 reference

12 December 2020

Nitric oxide production by cultured human aortic smooth muscle cells: stimulation by fluid flow

1 reference

12 December 2020

Impaired reactivity of rat aorta to phenylephrine and KCl after prolonged hypoxia: role of the endothelium

1 reference

12 December 2020

Enhancement of aortic contractility by endothelin following prolonged hypoxia in vivo

1 reference

12 December 2020

Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase

1 reference

12 December 2020

Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms

1 reference

12 December 2020

Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung

1 reference

12 December 2020

Hypoxia-induced protein binding to O2-responsive sequences on the tyrosine hydroxylase gene

1 reference

12 December 2020

NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death

1 reference

12 December 2020

Nitric oxide binding to the heme of neuronal nitric-oxide synthase links its activity to changes in oxygen tension

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI20806

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16276418%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference