(Q24294367)

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mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis

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mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis (English)

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mechanistic target of rapamycin kinase

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GOA release 2020-03-11

Tumor protein p53 inducible nuclear protein 2

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GOA release 2020-03-11

tuberous sclerosis

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based on heuristic

inferred from title

author name string

Shireena A Yasin

1

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Abu M Ali

2

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Mathew Tata

3

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Simon R Picker

4

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Glenn W Anderson

5

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Elizabeth Latimer-Bowman

6

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Sarah L Nicholson

7

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William Harkness

8

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J Helen Cross

9

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Simon M L Paine

10

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Thomas S Jacques

11

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language of work or name

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publication date

August 2013

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Acta Neuropathologica

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126

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207-18

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2

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https://scigraph.springernature.com/pub.10.1007/s00401-013-1135-4

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Insulin withdrawal-induced cell death in adult hippocampal neural stem cells as a model of autophagic cell death

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Identification of a novel modulator of thyroid hormone receptor-mediated action

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

mTOR cascade activation distinguishes tubers from focal cortical dysplasia

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Focal cortical dysplasia of Taylor's balloon cell type: mutational analysis of the TSC1 gene indicates a pathogenic relationship to tuberous sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Detection of human papillomavirus in human focal cortical dysplasia type IIB.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Internexin, MAP1B, and nestin in cortical dysplasia as markers of developmental maturity.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

mTOR: A pathogenic signaling pathway in developmental brain malformations

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Evolving neurobiology of tuberous sclerosis complex

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Autophagy: cellular and molecular mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Selective degradation of p62 by autophagy

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Possible mechanisms of disease development in tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Epilepsy in young people: 23 year follow up of the British national child development study

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Activation of mammalian target of rapamycin in cytomegalic neurons of human cortical dysplasia.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Hamartin variants that are frequent in focal dysplasias and cortical tubers have reduced tuberin binding and aberrant subcellular distribution in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

DOR undergoes nucleo-cytoplasmic shuttling, which involves passage through the nucleolus

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Suppressed expression of autophagosomal protein LC3 in cortical tubers of tuberous sclerosis complex.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Insulin signaling pathways in cortical dysplasia and TSC-tubers: tissue microarray analysis.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Simultaneous loss of hamartin and tuberin from the cerebrum, kidney and heart with tuberous sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Loss of tuberin from cerebral tissues with tuberous sclerosis and astrocytoma.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Differential Pi3K-pathway activation in cortical tubers and focal cortical dysplasias with balloon cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Alterations of phosphatidylinositol 3-kinase pathway components in epilepsy-associated glioneuronal lesions

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Focal cortical dysplasia of Taylor's balloon cell type: a clinicopathological entity with characteristic neuroimaging and histopathological features, and favorable postsurgical outcome.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Balloon cells in human cortical dysplasia and tuberous sclerosis: isolation of a pathological progenitor-like cell.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Termination of autophagy and reformation of lysosomes regulated by mTOR

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Developmental lineage of cell types in cortical dysplasia with balloon cells

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

21 January 2018

Expression of Neural Stem Cell Surface Marker CD133 in Balloon Cells of Human Focal Cortical Dysplasia

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1135-4

7 January 2021

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