(Q24294387)

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The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24720730%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24720730%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Alzheimer's disease

1 reference

based on heuristic

inferred from title

Amyloid beta precursor protein

1 reference

GOA release 2020-03-11

identical protein binding

1 reference

GOA release 2020-03-11

2

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Europe PubMed Central

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13 March 2020

author name string

Yu-Jen Chang

1

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13 March 2020

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publication date

6 May 2014

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Europe PubMed Central

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13 March 2020

1 reference

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13 March 2020

281

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13 March 2020

2674-2687

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Europe PubMed Central

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13 March 2020

11

1 reference

Europe PubMed Central

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13 March 2020

Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Deciphering the genetic basis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta-protein assembly and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Structural characterization of a soluble amyloid beta-peptide oligomer.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Polymorphism in the intermediates and products of amyloid assembly

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

The Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR study

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: stable trimer or tetramer formation by Abeta42.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Characterizations of distinct amyloidogenic conformations of the Abeta (1-40) and (1-42) peptides.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta protein: Abeta40 inhibits Abeta42 oligomerization

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Interaction between A beta(1-42) and A beta(1-40) in Alzheimer's beta-amyloid fibril formation in vitro.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Abeta40 inhibits amyloid deposition in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Variable deposition of amyloid beta-protein (A beta) with the carboxy-terminus that ends at residue valine40 (A beta 40) in the cerebral cortex of patients with Alzheimer's disease: a double-labeling immunohistochemical study with antibodies specifi

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Review: sporadic cerebral amyloid angiopathy

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Structure-neurotoxicity relationships of amyloid beta-protein oligomers

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Quartz crystal microbalance analysis of growth kinetics for aggregation intermediates of the amyloid-beta protein

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Two distinct amyloid beta-protein (Abeta) assembly pathways leading to oligomers and fibrils identified by combined fluorescence correlation spectroscopy, morphology, and toxicity analyses

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Activation of microglial cells by PrP and beta-amyloid fragments raises intracellular calcium through L-type voltage sensitive calcium channels.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

21 January 2018

Abeta40 protects non-toxic Abeta42 monomer from aggregation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

7 January 2021

based on heuristic

inferred from DOI database lookup

Fibrillar Abeta (1-42) enhances NMDA receptor sensitivity via the integrin signaling pathway.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12813

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1111/FEBS.12813

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24720730%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24720730%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

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