(Q24295036)

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ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses

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ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses (English)

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Interferon stimulated exonuclease gene 20

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GOA release 2020-03-11

response to virus

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GOA release 2020-03-11

author name string

Lucile Espert

1

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Genevieve Degols

2

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Celine Gongora

3

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Danielle Blondel

4

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Bryan R Williams

5

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Robert H Silverman

6

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Nadir Mechti

7

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language of work or name

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publication date

2 May 2003

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Journal of Biological Chemistry

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278

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18

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16151-8

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Tumor-suppressor genes: news about the interferon connection

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The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation

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Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway

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Antigen presentation by MHC class I and its regulation by interferon gamma

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Regulation of MHC class II genes: lessons from a disease

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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

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Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action

1 reference

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How cells respond to interferons

1 reference

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The Double-Stranded RNA-Dependent Protein Kinase PKR: Structure and Function

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Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

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Molecular Cloning of a New Interferon-induced PML Nuclear Body-associated Protein

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Assignment of ISG20 encoding a new interferon-induced PML nuclear body-associated protein, to chromosome 15q26 by in situ hybridization

1 reference

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The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains

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The human interferon- and estrogen-regulated ISG20/HEM45 gene product degrades single-stranded RNA and DNA in vitro

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Transcriptional and post-transcriptional regulation of c-myc expression during the differentiation of murine erythroleukemia Friend cells

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A unique ISRE, in the TATA-less human Isg20 promoter, confers IRF-1-mediated responsiveness to both interferon type I and type II.

1 reference

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Regulation of c-fos gene expression in hamster fibroblasts: initiation and elongation of transcription and mRNA degradation

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Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

1 reference

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Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

1 reference

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Antiviral actions of interferons

1 reference

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PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependent

1 reference

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Effect of deficiency of the double-stranded RNA-dependent protein kinase, PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to deficiency of the major IFN-mediated enzymes.

1 reference

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The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.

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The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysis

1 reference

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Specific cleavage of hyper-edited dsRNAs

1 reference

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Mechanism of interferon action: double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons

1 reference

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RNA editing by adenosine deaminases that act on RNA

1 reference

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A ribonuclease specific for inosine-containing RNA: a potential role in antiviral defence?

1 reference

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Lysozyme and RNases as anti-HIV components in beta-core preparations of human chorionic gonadotropin

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Interferon Enhances the Activity of the Anticancer Ribonuclease, Onconase

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Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells

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RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response

1 reference

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Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

1 reference

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HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes.

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Signatures of the immune response

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Human macrophage activation programs induced by bacterial pathogens

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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

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Interferon-γ Sensitizes Human Myeloid Leukemia Cells to Death Receptor-mediated Apoptosis by a Pleiotropic Mechanism

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Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

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Identifiers

10.1074/JBC.M209628200

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