(Q24295077)

sequence-specific DNA binding

GOA release 2020-03-11

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GOA release 2020-03-11

5

Matthew R Redinbo

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author name string

Isaac H Solomon

1

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Janet M Hager

2

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Rachid Safi

3

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Donald P McDonnell

4

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Eric A Ortlund

Journal of Molecular Biology

6

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language of work or name

English

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publication date

16 December 2005

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published in

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volume

354

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page(s)

1091-102

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issue

5

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cites work

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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

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Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation

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Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1

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LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis

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Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition

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Structural elements of an orphan nuclear receptor-DNA complex

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Structural determinants of nuclear receptor assembly on DNA direct repeats

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DNA-binding mechanism of the monomeric orphan nuclear receptor NGFI-B

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Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

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LRH-1/hB1F and HNF1 synergistically up-regulate hepatitis B virus gene transcription and DNA replication

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A functionally conserved member of the FTZ-F1 nuclear receptor family from Schistosoma mansoni

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Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner

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Multiprotein bridging factor 1 (MBF1) is an evolutionarily conserved transcriptional coactivator that connects a regulatory factor and TATA element-binding protein

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A naturally occurring steroidogenic factor-1 mutation exhibits differential binding and activation of target genes

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The C-terminal extension (CTE) of the nuclear hormone receptor DNA binding domain determines interactions and functional response to the HMGB-1/-2 co-regulatory proteins.

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Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes

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The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element

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Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1

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Structural basis of VDR-DNA interactions on direct repeat response elements

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A sequence-specific DNA-binding protein that activates fushi tarazu segmentation gene expression.

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Improved methods for building protein models in electron density maps and the location of errors in these models

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An approach to multi-copy search in molecular replacement

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A novel DNA-binding motif abuts the zinc finger domain of insect nuclear hormone receptor FTZ-F1 and mouse embryonal long terminal repeat-binding protein

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The DNA-bending protein HMG-1 enhances progesterone receptor binding to its target DNA sequences

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The alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family

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High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells

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Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development

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7 January 2021

Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer

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7 January 2021

Steroidogenic factor 1: a key determinant of endocrine development and function

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7 January 2021

Gonadal determination and adrenal development are regulated by the orphan nuclear receptor steroidogenic factor-1, in a dose-dependent manner.

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7 January 2021

The high mobility group protein 1 enhances binding of the estrogen receptor DNA binding domain to the estrogen response element.

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7 January 2021

Molecular mechanism for the potentiation of the transcriptional activity of human liver receptor homolog 1 by steroid receptor coactivator-1.

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7 January 2021