(Q24295201)

6 July 2017

title

Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors (English)

1 reference

6 July 2017

Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M310301200

14 March 2024

0 references

1 reference

GOA release 2020-03-11

digestion

1 reference

GOA release 2020-03-11

1 reference

https://api.crossref.org/works/10.1074/JBC.M310301200

14 March 2024

3

Miklos Sahin-Tóth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507909

14 March 2024

author name string

Richárd Szmola

series ordinal

1

1 reference

6 July 2017

Zoltán Kukor

series ordinal

2

1 reference

6 July 2017

language of work or name

English

0 references

publication date

24 September 2003

1 reference

full work available at URL

6 July 2017

http://www.jbc.org/article/S002192582075619X/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507909

https://europepmc.org/articles/PMC1393292

14 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507909

https://europepmc.org/articles/PMC1393292?pdf=render

14 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507909

https://doi.org/10.1074/jbc.m310301200

14 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507909

https://api.elsevier.com/content/article/PII:S002192582075619X?httpAccept=text/xml

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310301200

https://api.elsevier.com/content/article/PII:S002192582075619X?httpAccept=text/plain

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310301200

https://syndication.highwire.org/content/doi/10.1074/jbc.M310301200

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M310301200

Journal of Biological Chemistry

14 March 2024

published in

1 reference

6 July 2017

volume

278

1 reference

6 July 2017

issue

49

1 reference

6 July 2017

page(s)

48580-48589

1 reference

Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases

6 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Identification and expression of the cDNA-encoding human mesotrypsin(ogen), an isoform of trypsin with inhibitor resistance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Cloning of the cDNA encoding human brain trypsinogen and characterization of its product

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Crystal structure reveals basis for the inhibitor resistance of human brain trypsin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

What can the structures of enzyme-inhibitor complexes tell us about the structures of enzyme substrate complexes?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Trypsinogen variants in pancreatic juice of healthy volunteers, chronic alcoholics, and patients with pancreatitis and cancer of the pancreas

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Hereditary pancreatitis-associated mutation asn(21) --> ile stabilizes rat trypsinogen in vitro

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Thermodynamics and kinetics of the hydrolysis of the reactive-site peptide bond in pancreatic trypsin inhibitor (Kunitz) by Dermasterias imbricata trypsin 1

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Detailed mechanism of interaction of bovine -trypsin with soybean trypsin inhibitor (Kunitz). I. Stopped flow measurements

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Site-directed mutagenesis of human pancreatic secretory trypsin inhibitor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Sequence of Tryptic Cleavages in Porcine Pancreatic Secretory Inhibitor II

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1393292

Affinity purification of recombinant trypsinogen using immobilized ecotin.

19 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310301200

Comparative in vitro studies on native and recombinant human cationic trypsins. Cathepsin B is a possible pathological activator of trypsinogen in pancreatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310301200

Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310301200

Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310301200

Expression and functional analysis of rat P23, a gut hormone-inducible isoform of trypsin, reveals its resistance to proteinaceous trypsin inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310301200

p-Nitrophenyl-p'-guanidinobenzoate HCl: a new active site titrant for trypsin

21 January 2018

1 reference

12 December 2020

Occurrence of two cleavages preceding inactivation of bovine temporary trypsin isoinhibitor A

1 reference

12 December 2020

Dermasterias imbricata trypsin 1: an enzyme which rapidly hydrolyzes the reactive-site peptide bonds of protein trypsin inhibitors

1 reference

12 December 2020

Effects of chronic alcohol abuse on exocrine pancreatic secretion in man

1 reference

12 December 2020

Possible lysosomal activation of pancreatic zymogens. Activation of both human trypsinogens by cathepsin B and spontaneous acid. Activation of human trypsinogen 1

1 reference

12 December 2020

Temporary inhibition of trypsin

1 reference

12 December 2020

Identifiers

1 reference

release_j2o6633h4fahfj3jzt2waq3jky

6 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/j2o6633h4fahfj3jzt2waq3jky

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1393292

1 reference

6 July 2017

1 reference