(Q24295552)

English

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB

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scholarly article

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The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB (English)

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apoptotic process

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Protein inhibitor of activated STAT 4

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GOA release 2020-03-11

Tripartite motif containing 32

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GOA release 2020-03-11

ubiquitin protein ligase binding

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GOA release 2020-03-11

Tripartite motif-containing 32

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GOA release 2020-03-11

Protein inhibitor of activated STAT 4

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GOA release 2020-03-11

Protein inhibitor of activated STAT 2

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GOA release 2020-03-11

Protein inhibitor of activated STAT 1

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

limb-girdle muscular dystrophy

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based on heuristic

inferred from title

author name string

Amador Albor

1

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Sally El-Hizawi

2

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Elizabeth J Horn

3

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Melanie Laederich

4

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Patrick Frosk

5

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Klaus Wrogemann

6

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Molly Kulesz-Martin

7

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language of work or name

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publication date

1 September 2006

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Journal of Biological Chemistry

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281

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35

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25850-66

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The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The tripartite motif family identifies cell compartments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

A novel repeat domain that is often associated with RING finger and B-box motifs.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Novel tumorigenic rearrangement, Delta rfp/ret, in a papillary thyroid carcinoma from externally irradiated patient

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Activation of a novel human transforming gene, ret, by DNA rearrangement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The most common mutation in FKRP causing limb girdle muscular dystrophy type 2I (LGMD2I) may have occurred only once and is present in Hutterites and other populations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

SUMO: a regulator of gene expression and genome integrity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Nuclear and unclear functions of SUMO

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

SAP - a putative DNA-binding motif involved in chromosomal organization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Regulation of gene-activation pathways by PIAS proteins in the immune system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Cloning and analysis of a murine PIAS family member, PIASgamma, in developing skin and neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

PIASy-deficient mice display modest defects in IFN and Wnt signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

A Drosophila PIAS homologue negatively regulates stat92E

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The UCSC Genome Browser Database

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

PML protein isoforms and the RBCC/TRIM motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

A putative protein inhibitor of activated STAT (PIASy) interacts with p53 and inhibits p53-mediated transactivation but not apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Involvement of PIAS1 in the sumoylation of tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 is a transcriptional cofactor for TFII-I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Analysis and prediction of leucine-rich nuclear export signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

NESbase version 1.0: a database of nuclear export signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

NLSdb: database of nuclear localization signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Yeast PIAS-type Ull1/Siz1 is composed of SUMO ligase and regulatory domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Pathway-specific profiling identifies the NF-kappa B-dependent tumor necrosis factor alpha-regulated genes in epidermal keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Apoptosis in proliferating, senescent, and immortalized keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The mei-P26 gene encodes a RING finger B-box coiled-coil-NHL protein that regulates seizure susceptibility in Drosophilia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

DNA microarray analysis of stage progression mechanism in myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

The ‘PINIT’ motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Commonality of TRIM32 mutation in causing sarcotubular myopathy and LGMD2H.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Pathophysiology of limb girdle muscular dystrophy type 2A: hypothesis and new insights into the IkappaBalpha/NF-kappaB survival pathway in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IκBα/NF-κB pathway in limb-girdle muscular dystrophy type 2A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601655200

21 January 2018

Benign and malignant tumor stages in a mouse keratinocyte line treated with 7,12-dimethylbenz[a]anthracene in vitro

1 reference

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7 January 2021

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10.1074/JBC.M601655200

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