(Q21498896)

Six-bladed beta-propeller, TolB-like

1 reference

RING-type zinc-finger, LisH dimerisation motif, protein family

1 reference

B-box-type zinc finger, protein family

1 reference

Zinc finger, RING-type, protein family

1 reference

Zinc finger, RING-type, conserved site, protein family

1 reference

NHL repeat domain, protein family

1 reference

ubiquitin protein ligase activity

1 reference

25 May 2022

1 reference

25 May 2022

5 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

ubiquitin-protein transferase activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

The tripartite motif family identifies cell compartments

protein self-association

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

translation initiation factor binding

1 reference

14 February 2019

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

ubiquitin protein ligase activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

intracellular anatomical structure

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

striated muscle myosin thick filament

1 reference

14 February 2019

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

The tripartite motif family identifies cell compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of interleukin-17-mediated signaling pathway

biological process

1 reference

14 February 2019

Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of cell motility

1 reference

14 February 2019

Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of protein catabolic process

muscle cell cellular homeostasis

1 reference

14 February 2019

The common missense mutation D489N in TRIM32 causing limb girdle muscular dystrophy 2H leads to loss of the mutated protein in knock-in mice resulting in a Trim32-null phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of tumor necrosis factor-mediated signaling pathway

1 reference

14 February 2019

Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of cell migration

protein polyubiquitination

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

negative regulation of keratinocyte apoptotic process

1 reference

14 February 2019

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

response to tumor necrosis factor

NAS

1 reference

14 February 2019

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of neurogenesis

1 reference

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of cell growth

positive regulation of cell cycle

positive regulation of NF-kappaB transcription factor activity

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

27 March 2018

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CH72&geneProductId=UniProtKB:Q8CH72

protein ubiquitination

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of neuron differentiation

1 reference

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of striated muscle cell differentiation

1 reference

14 February 2019

TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of proteolysis

negative regulation of fibroblast proliferation

1 reference

14 February 2019

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of chemokine (C-C motif) ligand 20 production

IEP

1 reference

14 February 2019

Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

Temporal expression pattern of Bardet-Biedl syndrome genes in adipogenesis

fat cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

1 reference

14 February 2019

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

ubiquitin-dependent protein catabolic process

protein polyubiquitination

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

positive regulation of NF-kappaB transcription factor activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

protein K48-linked ubiquitination

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CH72

RING-type zinc-finger, LisH dimerisation motif

has part(s)

1 reference

Zinc finger, RING-type, conserved site

1 reference

Zinc finger, RING-type

1 reference

NHL repeat

1 reference

B-box-type zinc finger

1 reference