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FAM83B mediates EGFR- and RAS-driven oncogenic transformation
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instance of
scholarly article
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title
FAM83B mediates EGFR- and RAS-driven oncogenic transformation
(English)
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main subject
Family with sequence similarity 83 member B
1 reference
stated in
GOA release 2020-03-11
phospholipase D activity
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stated in
GOA release 2020-03-11
author
Benjamin L. Bryson
object named as
Benjamin L Bryson
series ordinal
4
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author name string
Rocky Cipriano
series ordinal
1
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James Graham
series ordinal
2
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Kristy L S Miskimen
series ordinal
3
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Ronald C Bruntz
series ordinal
5
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Sarah A Scott
series ordinal
6
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H Alex Brown
series ordinal
7
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George R Stark
series ordinal
8
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Mark W Jackson
series ordinal
9
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language of work or name
English
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publication date
September 2012
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published in
Journal of Clinical Investigation
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volume
122
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issue
9
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page(s)
3197-210
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cites work
FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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19 March 2017
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling
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PubMed Central
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19 March 2017
BJ-TSA-9, a novel human tumor-specific gene, has potential as a biomarker of lung cancer
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PubMed Central
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19 March 2017
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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19 March 2017
A genetic screen for candidate tumor suppressors identifies REST
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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19 March 2017
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis
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PubMed Central
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19 March 2017
Phospholipase D in cell proliferation and cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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19 March 2017
Targeting RAS signalling pathways in cancer therapy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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19 March 2017
Raf-1 activates MAP kinase-kinase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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19 March 2017
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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7 April 2017
The RAF proteins take centre stage
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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7 April 2017
TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells
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PubMed Central
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27 September 2017
Significance of Tyrosine Kinase Inhibitors in the Treatment of Metastatic Breast Cancer
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PubMed Central
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27 September 2017
Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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27 September 2017
Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB.
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PubMed Central
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27 September 2017
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness
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PubMed Central
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27 September 2017
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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27 September 2017
Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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27 September 2017
Epigenetic inactivation of the HOXA gene cluster in breast cancer
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PubMed Central
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27 September 2017
Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.
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PubMed Central
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27 September 2017
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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27 September 2017
MdmX protects p53 from Mdm2-mediated degradation
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stated in
PubMed Central
reference URL
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27 September 2017
p53-mediated growth suppression in response to Nutlin-3 in cyclin D1 transformed cells occurs independently of p21.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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30 May 2018
Association of N- and C-terminal domains of phospholipase D is required for catalytic activity
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
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30 May 2018
Biochemical analysis of phospholipase D.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428078
retrieved
29 November 2018
Epidermal growth factor receptor expression as a prognostic indicator in breast cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22886302
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22886302
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI60517
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4825196
OpenCitations bibliographic resource ID
4825196
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4825196
PMCID
3428078
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4825196
PubMed ID
22886302
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4825196
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