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A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
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scholarly article
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PubMed
PubMed ID
22072986
retrieved
12 December 2016
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
title
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
main subject
regulation of protein localization to ciliary membrane
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1903567
regulation of protein localization to cilium
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1903564
negative regulation of protein localization to cilium
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1903565
negative regulation of protein localization to ciliary membrane
2 references
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1903568
stated in
GOA release 2020-03-11
positive regulation of protein localization to ciliary membrane
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1903569
positive regulation of protein localization to cilium
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1903566
Leucine zipper transcription factor like 1
1 reference
stated in
GOA release 2020-03-11
Bardet-Biedl syndrome 1 (human)
1 reference
stated in
GOA release 2020-03-11
Leucine zipper transcription factor-like 1
1 reference
stated in
GOA release 2020-03-11
Bardet-Biedl syndrome 7 (human)
1 reference
stated in
GOA release 2020-03-11
Tetratricopeptide repeat domain 8
1 reference
stated in
GOA release 2020-03-11
Bardet-Biedl syndrome 4 (human)
1 reference
stated in
GOA release 2020-03-11
Bardet-Biedl syndrome 9 (human)
1 reference
stated in
GOA release 2020-03-11
Bardet-Biedl syndrome 2 (human)
1 reference
stated in
GOA release 2020-03-11
Bardet-Biedl syndrome 5 (human)
1 reference
stated in
GOA release 2020-03-11
author
David K. Breslow
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Charles C Searby
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Seongjin Seo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Maxence V. Nachury
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Val C Sheffield
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author name string
Qihong Zhang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Kevin Bugge
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
language of work or name
English
0 references
publication date
3 November 2011
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
published in
PLOS Genetics
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
volume
7
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
page(s)
e1002358
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
copyright license
Creative Commons Attribution 4.0 International
start time
3 November 2011
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
A BBSome subunit links ciliogenesis, microtubule stability, and acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
The Ciliopathies: An Emerging Class of Human Genetic Disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Self-association of the H3 region of syntaxin 1A. Implications for intermediates in SNARE complex assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Tumor-suppressive functions of leucine zipper transcription factor-like 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Sensory ciliogenesis in Caenorhabditis elegans: assignment of IFT components into distinct modules based on transport and phenotypic profiles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Vertebrate Smoothened functions at the primary cilium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
The LZTFL1 gene is a part of a transcriptional map covering 250 kb within the common eliminated region 1 (C3CER1) in 3p21.3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
19 March 2017
The primary cilium: a signalling centre during vertebrate development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
7 April 2017
InterProScan--an integration platform for the signature-recognition methods in InterPro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
7 April 2017
CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
7 April 2017
Direct observation of individual endogenous protein complexes in situ by proximity ligation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
7 April 2017
The primary cilium as the cell's antenna: signaling at a sensory organelle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
7 April 2017
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
27 September 2017
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207910
retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002358
retrieved
21 January 2018
Intraflagellar transport is essential for endochondral bone formation.
1 reference
stated in
Crossref
reference URL
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retrieved
21 January 2018
Identifiers
DOI
10.1371/JOURNAL.PGEN.1002358
1 reference
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PMCID
3207910
2 references
stated in
PubMed
PubMed ID
22072986
retrieved
12 December 2016
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PubMed ID
22072986
2 references
stated in
PubMed
PubMed ID
22072986
retrieved
12 December 2016
stated in
Europe PubMed Central
PMCID
3207910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
ResearchGate publication ID
51786448
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