(Q24297078)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

An RNA virus hijacks an incognito function of a DNA repair enzyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

tyrosyl-RNA phosphodiesterase activity

11 February 2020

main subject

virology

0 references

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0036317

Tyrosyl-DNA phosphodiesterase 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Richard Virgen-Slane

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Tuan Ngo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

Gerbrand J van der Heden van Noort

11 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

9

Bert L Semler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2

Janet M Rozovics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Kerry D Fitzgerald

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Wayne Chou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Dmitri V Filippov

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Paul D Gershon

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

20 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

11 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

36

1 reference

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11 February 2020

page(s)

14634-14639

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

The structure of a protein primer-polymerase complex in the initiation of genome replication

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Sequence analysis identifies TTRAP, a protein that associates with CD40 and TNF receptor-associated factors, as a member of a superfamily of divalent cation-dependent phosphodiesterases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

EAPII interacts with ETS1 and modulates its transcriptional function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Pleiotropic functions of EAPII/TTRAP/TDP2: cancer development, chemoresistance and beyond

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Development of a novel assay for human tyrosyl DNA phosphodiesterase 2

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Virology, epidemiology, pathogenesis, and control of enterovirus 71.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Role of viral respiratory infections in asthma and asthma exacerbations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Recognition of mRNA cap structures by viral and cellular proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

VPg unlinkase, the phosphodiesterase that hydrolyzes the bond between VPg and picornavirus RNA: a minimal nucleic moiety of the substrate

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Cation-pi interactions in ligand recognition and catalysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Functional coupling between replication and packaging of poliovirus replicon RNA

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Natural covalent complexes of nucleic acids and proteins: some comments on practice and theoryon the path from well-known complexes to new ones

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

Removal of the genome-linked protein of foot-and-mouth disease virus by rabbit reticulocyte lysate.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

An enzymatic activity in uninfected cells that cleaves the linkage between poliovirion RNA and the 5′ terminal protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

The 5'-terminal structures of poliovirion RNA and poliovirus mRNA differ only in the genome-linked protein VPg

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437895

A phosphodiesterase from ascites carcinoma Krebs II cells specifically cleaves the bond between VPg and RNA of encephalomyocarditis virus.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1208096109

Isolation from ascites carcinoma Krebs II cells of an unlinking enzyme hydrolyzing a covalent bond between picornavirus RNA and VPg

21 January 2018

1 reference

12 December 2020

Purification and properties of a HeLa cell enzyme able to remove the 5'-terminal protein from poliovirus RNA

1 reference

12 December 2020

The fate of VPg during in vitro translation of poliovirus RNA

1 reference

12 December 2020

An enzyme which specifically splits a covalent bond between picornaviral RNA and VPg

1 reference

12 December 2020

[Natural substrates of uridylylpolynucleotide-(5'P--->O)-tyrosine phosphodiesterase--an enzyme, hydrolyzing the covalent bond between RNA and picornaviral VPg and a synthetic model of them]

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1208096109

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

ADS bibcode

2012PNAS..10914634V

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22908287%20AND%20SRC:MED&resulttype=core&format=json