(Q24297544)

English

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

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Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme (English)

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cytochrome P450 family 3 subfamily A member 4

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GOA release 2020-03-11

testosterone 6-beta-hydroxylase activity

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GOA release 2020-03-11

author name string

D J Waxman

1

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C Attisano

2

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F P Guengerich

3

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D P Lapenson

4

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language of work or name

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publication date

June 1988

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Archives of Biochemistry and Biophysics

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263

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2

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424-36

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Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450.

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Isozyme specificity of testosterone 7 alpha-hydroxylation in rat hepatic microsomes: is cytochrome P-450a the sole catalyst?

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Testosterone oxidation by rat liver microsomes: Effects of phenobarbital pretreatment and the detection of seven metabolites by HPLC

1 reference

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Inactivation of rat hepatic cytochrome P-450 by spironolactone

1 reference

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Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man

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Preparation and characterization of monoclonal antibodies to pregnenolone 16-alpha-carbonitrile inducible rat liver cytochrome P-450.

1 reference

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Significance of cytochrome P-450 (P-450 HFLa) of human fetal livers in the steroid and drug oxidations

1 reference

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Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression

1 reference

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7 January 2021

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Purification and characterization of six cytochrome P-450 isozymes from human liver microsomes

1 reference

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Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

1 reference

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Evidence for functional and structural multiplicity of pregnenolone-16 alpha-carbonitrile-inducible cytochrome P-450 isozymes in rat liver microsomes

1 reference

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Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

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Immunochemical evidence for multiple steroid-inducible hepatic cytochromes P-450 in the rat.

1 reference

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The P450 gene superfamily: recommended nomenclature.

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Effect of growth hormone and ectopic transplantation of pituitary gland on sex-specific forms of cytochrome P-450 and testosterone and drug oxidations in rat liver.

1 reference

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Assessment of urinary 6 beta-hydroxycortisol as an in vivo index of mixed-function oxygenase activity

1 reference

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Cytochrome P-450 monooxygenase activities in human and rat liver microsomes

1 reference

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7 January 2021

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Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

1 reference

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7 January 2021

based on heuristic

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The regulation of cytochrome P-450 gene expression

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The physiologic significance of 6beta-hydroxycortisol in human corticoid metabolism

1 reference

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7 January 2021

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Metabolism of 2-alpha- and 6-beta-hydroxycortisol in man: determination of production rates of 6-beta-hydroxycortisol with and without phenobarbital administration

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/0003-9861(88)90655-8

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