(Q24297864)

1

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Tappei Takada

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Jun-Ichi Shoda

3

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Hiroshi Suzuki

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

4

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language of work or name

English

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publication date

March 2012

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published in

Hepatology

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volume

55

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page(s)

953-64

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issue

3

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cites work

1 reference

Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.

21 January 2018

1 reference

Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

21 January 2018

1 reference

Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population

21 January 2018

1 reference

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

21 January 2018

1 reference

Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1.

21 January 2018

1 reference

Niemann-Pick disease type C.

21 January 2018

1 reference

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

1 reference

Identification of HE1 as the second gene of Niemann-Pick C disease

21 January 2018

1 reference

Structure and function of the NPC2 protein

21 January 2018

1 reference

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

21 January 2018

1 reference

Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes

21 January 2018

1 reference

NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis

21 January 2018

1 reference

NPC2 regulates biliary cholesterol secretion via stimulation of ABCG5/G8-mediated cholesterol transport

21 January 2018

1 reference

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

21 January 2018

1 reference

Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?

21 January 2018

1 reference

Niemann-pick C1-like 1 mediates alpha-tocopherol transport

21 January 2018

1 reference

In-vitro characterization of the six clustered variants of NPC1L1 observed in cholesterol low absorbers

21 January 2018

1 reference

Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4

21 January 2018

1 reference

Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking

21 January 2018

1 reference

Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells

21 January 2018

1 reference

Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein

21 January 2018

1 reference

Secretion of sterols and the NPC2 protein from primary astrocytes

21 January 2018

1 reference

Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation

21 January 2018

1 reference

The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.

21 January 2018

1 reference

Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells

21 January 2018

1 reference

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

21 January 2018

1 reference

Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.

21 January 2018

1 reference

HNF4alpha is a crucial modulator of the cholesterol-dependent regulation of NPC1L1.

21 January 2018

1 reference

NPC1 and NPC2 Regulate Cellular Cholesterol Homeostasis through Generation of Low Density Lipoprotein Cholesterol-derived Oxysterols

21 January 2018

1 reference

Localization and role of NPC1L1 in cholesterol absorption in human intestine

21 January 2018

1 reference

Absorption, metabolism, and serum concentrations of cholesterol in vegetarians: effects of cholesterol feeding

21 January 2018

1 reference