(Q33227195)

24 July 2017

Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells (English)

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Niemann–Pick disease, type C

24 July 2017

1 reference

1 reference

based on heuristic

inferred from title

author

Frederick R. Maxfield

object named as

Frederick R Maxfield

5

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author name string

Nina H Pipalia

1

1 reference

24 July 2017

Amy Huang

2

1 reference

24 July 2017

Harold Ralph

3

1 reference

24 July 2017

Madalina Rujoi

4

1 reference

24 July 2017

15 November 2005

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Journal of Lipid Research

24 July 2017

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24 July 2017

47

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24 July 2017

284-301

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24 July 2017

2

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Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

24 July 2017

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Therapy of Niemann-Pick disease, type C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Critical issues in gene therapy for neurologic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Identification of a pharmaceutical compound that partially corrects the Niemann-Pick C phenotype in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Critical role for glycosphingolipids in Niemann-Pick disease type C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Lipoprotein receptors and the control of plasma LDL cholesterol levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

The Niemann-Pick C proteins and trafficking of cholesterol through the late endosomal/lysosomal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Niemann-Pick type C mutations cause lipid traffic jam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

The structure and function of the Niemann-Pick C1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

The NPC1 protein: structure implies function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Structure and function of the NPC2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Lipid and cholesterol trafficking in NPC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Human acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site location

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Identification of 58 novel mutations in Niemann-Pick disease type C: correlation with biochemical phenotype and importance of PTC1-like domains in NPC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Six novel NPC1 mutations in Chinese patients with Niemann-Pick disease type C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Niemann-Pick disease type C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Clinical-biochemical correlation in molecularly characterized patients with Niemann-Pick type C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Cholesterol trafficking in the secretory and endocytic systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Chemical Similarity Searching

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

H2-antihistaminics. 31. 1,2,5-Triazine-2,4-diamines and -2,4,6-triamines with H2-antagonistic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Advances in Na(+)/I(-) symporter (NIS) research in the thyroid and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Role of ABCA1 in cellular cholesterol efflux and reverse cholesterol transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Elevated endosomal cholesterol levels in Niemann-Pick cells inhibit rab4 and perturb membrane recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

Synthesis, structural characterization and antitumor activity of novel 2,4-diamino-1,3,5-triazine derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500388-JLR200

10.1194/JLR.M500388-JLR200

21 January 2018

Identifiers

DOI

1 reference

24 July 2017

1 reference