(Q24298309)

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BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response

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BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response (English)

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Bardet-Biedl syndrome 12

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GOA release 2020-03-11

negative regulation of fat cell differentiation

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GOA release 2020-03-11

Bardet-Biedl syndrome 12 (human)

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GOA release 2020-03-11

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inferred from title

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Hélène Dollfus

15

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Nadia Messaddeq

7

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Nikolai Petrovsky

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Nikolai Petrovsky

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author name string

Vincent Marion

1

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Anaïs Mockel

2

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Charlie De Melo

3

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Cathy Obringer

4

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Aurélie Claussmann

5

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Alban Simon

6

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Myriam Durand

8

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Luc Dupuis

9

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Jean-Philippe Loeffler

10

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Peter King

11

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Catherine Mutter-Schmidt

12

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Corinne Stoetzel

14

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language of work or name

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publication date

5 September 2012

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Cell Metabolism

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16

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3

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363-77

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Ciliary biology: understanding the cellular and genetic basis of human ciliopathies

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153).

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: cross talk with the osteoblastogenic program

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Transverse and tangential orientation of predicted transmembrane fragments 4 and 10 from the human multidrug resistance protein (hMRP1/ABCC1) in membrane mimics

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Artepillin C, as a PPARγ ligand, enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Temporal expression pattern of Bardet-Biedl syndrome genes in adipogenesis

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Modeling human disease in humans: the ciliopathies

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Hedgehog signaling plays a conserved role in inhibiting fat formation

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Impairment of central leptin-mediated PI3K signaling manifested as hepatic steatosis independent of hyperphagia and obesity

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Retraction notice to: Impairment of central leptin-mediated PI3K signaling manifested as hepatic steatosis independent of hyperphagia and obesity

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Lifting the lid on Pandora's box: the Bardet-Biedl syndrome

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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The chemokine system in diverse forms of macrophage activation and polarization

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Retinal dystrophy in Bardet-Biedl syndrome and related syndromic ciliopathies

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Preadipocytes of type 2 diabetes subjects display an intrinsic gene expression profile of decreased differentiation capacity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Autosomal recessive Bardet-Biedl syndrome: first-degree relatives have no predisposition to metabolic and renal disorders.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Bardet–Biedl syndrome highlights the major role of the primary cilium in efficient water reabsorption

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Alström syndrome: insights into the pathogenesis of metabolic disorders

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Regulation of immune responses by L-arginine metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Monocyte and macrophage heterogeneity

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Alternative activation of macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Forming functional fat: a growing understanding of adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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In vivo phenotyping of the ob/ob mouse by magnetic resonance imaging and 1H-magnetic resonance spectroscopy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor gamma and sterol regulatory element-binding protein in the regulation of adipogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Obesity and the role of adipose tissue in inflammation and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Ciliary dysfunction and obesity

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Genetics. Mendelian puzzles

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https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Exome sequencing identifies mutations in LZTFL1, a BBSome and smoothened trafficking regulator, in a family with Bardet--Biedl syndrome with situs inversus and insertional polydactyly.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific removal of C-reactive protein by apheresis in a porcine cardiac infarction model

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Inflammation and insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Patients with Bardet-Biedl syndrome have hyperleptinemia suggestive of leptin resistance

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Fat aussie--a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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The primary cilium at a glance

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Differential effects of thiazolidinediones on adipocyte growth and recruitment in Zucker fatty rats

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Hedgehog signaling alters adipocyte maturation of human mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Can faulty antennae increase adiposity? The link between cilia proteins and obesity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator-activated receptor-gamma agonists and diabetes: current evidence and future perspectives

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Bardet-Biedl syndrome: a study of the renal and cardiovascular phenotypes in a French cohort

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

inferred from DOI database lookup

Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Differentiating Alström from Bardet-Biedl syndrome (BBS) using systematic ciliopathy genes sequencing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

based on heuristic

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Radial access in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty in acute myocardial infarction: the HORIZONS-AMI trial.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CMET.2012.08.005

7 January 2021

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10.1016/J.CMET.2012.08.005

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