(Q24298783)

English

Binding of urokinase-type plasminogen activator receptor (uPAR) to the mannose 6-phosphate/insulin-like growth factor II receptor: contrasting interactions of full-length and soluble forms of uPAR

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scholarly article

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Binding of urokinase-type plasminogen activator receptor (uPAR) to the mannose 6-phosphate/insulin-like growth factor II receptor: contrasting interactions of full-length and soluble forms of uPAR (English)

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Plasminogen activator, urokinase receptor

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GOA release 2020-03-11

protein domain specific binding

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

Jodi L Kreiling

1

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James C Byrd

2

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Robert J Deisz

3

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Ikuko F Mizukami

4

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Robert F Todd

5

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Richard G MacDonald

6

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language of work or name

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publication date

6 June 2003

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Journal of Biological Chemistry

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278

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23

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20628-37

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302249200

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Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognition

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Type-2 IGF receptor: a multi-ligand binding protein

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Localization of the insulin-like growth factor II binding site to amino acids 1508-1566 in repeat 11 of the mannose 6-phosphate/insulin-like growth factor II receptor

1 reference

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21 January 2018

An insulin-like growth factor II (IGF-II) affinity-enhancing domain localized within extracytoplasmic repeat 13 of the IGF-II/mannose 6-phosphate receptor

1 reference

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Real time kinetics of insulin-like growth factor II (IGF-II) interaction with the IGF-II/mannose 6-phosphate receptor: the effects of domain 13 and pH.

1 reference

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Localization of the carbohydrate recognition sites of the insulin-like growth factor II/mannose 6-phosphate receptor to domains 3 and 9 of the extracytoplasmic region

1 reference

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Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor

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Latent transforming growth factor-beta: structural features and mechanisms of activation

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The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

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Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality

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Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds

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M6P/IGF2R is mutated in squamous cell carcinoma of the lung

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Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations.

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Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells

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Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction

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The N terminus of mannose 6-phosphate/insulin-like growth factor 2 receptor in regulation of fibrinolysis and cell migration.

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Autocrine saturation of pro-urokinase receptors on human A431 cells.

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Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor

1 reference

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21 January 2018

uPAR: a versatile signalling orchestrator

1 reference

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Mechanisms for high affinity mannose 6-phosphate ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor

1 reference

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21 January 2018

Immunologic detection of the cellular receptor for urokinase plasminogen activator

1 reference

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Production of high-titer helper-free retroviruses by transient transfection

1 reference

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The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae

1 reference

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21 January 2018

Mannose-6-phosphate enhances cross-linking efficiency between insulin-like growth factor-II (IGF-II) and IGF-II/mannose-6-phosphate receptors in membranes

1 reference

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Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells

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Insulin-like growth factor II modulates the routing of cathepsin D in MCF-7 breast cancer cells

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Recognition of Dictyostelium discoideum lysosomal enzymes is conferred by the amino-terminal carbohydrate binding site of the insulin-like growth factor II/mannose 6-phosphate receptor

1 reference

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21 January 2018

The urokinase-type plasminogen activator system in cancer metastasis: a review

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Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration

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Insulin-like growth factor-II/mannose 6-phosphate receptor overexpression reduces growth of choriocarcinoma cells in vitro and in vivo

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21 January 2018

M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1

1 reference

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21 January 2018

Dimerization of the insulin-like growth factor II/mannose 6-phosphate receptor

1 reference

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Beta-galactosidase decreases the binding affinity of the insulin-like-growth-factor-II/mannose-6-phosphate receptor for insulin-like-growth-factor II

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M302249200

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