(Q24299827)

Eukaryotic translation initiation factor 5A

GOA release 2020-03-11

1 reference

positive regulation of cell population proliferation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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Paul M J Clement

1

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C Allen Henderson

2

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Zandra A Jenkins

3

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Zeljka Smit-McBride

4

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Edith C Wolff

5

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John W B Hershey

6

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Myung Hee Park

7

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Hans E Johansson

The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine

8

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language of work or name

English

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publication date

November 2003

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published in

FEBS Journal

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volume

270

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issue

21

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page(s)

4254-63

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cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

Interferon alpha2 recombinant and epidermal growth factor modulate proliferation and hypusine synthesis in human epidermoid cancer KB cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-alpha and EGF in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

Identification of a substrate site for transglutaminases on the human protein synthesis initiation factor 5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

Crystal structure of hyperthermophilic archaeal initiation factor 5A: a homologue of eukaryotic initiation factor 5A (eIF-5A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

Translational control of the proteome: relevance to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

The two genes encoding protein synthesis initiation factor eIF-5A in Saccharomyces cerevisiae are members of a duplicated gene cluster

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

The function of the hypusine-containing proteins of yeast and other eukaryotes is well conserved

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

The HYP2 gene of Saccharomyces cerevisiae is essential for aerobic growth: characterization of different isoforms of the hypusine-containing protein Hyp2p and analysis of gene disruption mutants

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

The role of eukaryotic initiation factor 5A in the control of cell proliferation and apoptosis.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Deoxyhypusine synthase gene is essential for cell viability in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Inhibition of the G1-S transition of the cell cycle by inhibitors of deoxyhypusine hydroxylation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Effects of inhibitors of deoxyhypusine synthase on the differentiation of mouse neuroblastoma and erythroleukemia cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Identification of a new member of the human eIF-5A gene family

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

The eukaryotic cofactor for the human immunodeficiency virus type 1 (HIV-1) rev protein, eIF-5A, maps to chromosome 17p12-p13: three eIF-5A pseudogenes map to 10q23.3, 17q25, and 19q13.2.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Malignant transformation by the eukaryotic translation initiation factor 3 subunit p48 (eIF3e).

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Recurrent chromosome alterations in primary ovarian carcinoma in Chinese women

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Aminohexanoic hydroxamate is a potent inducer of the differentiation of mouse neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Multiple sequence alignment with Clustal X

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 A resolution

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

PIK3CA as an oncogene in cervical cancer

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Modulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8 A resolution

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Cloning and expression of human deoxyhypusine synthase cDNA. Structure-function studies with the recombinant enzyme and mutant proteins

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Deoxyhypusine synthase activity is essential for cell viability in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

A single amino acid substitution in yeast eIF-5A results in mRNA stabilization

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Cell cycle arrest in archaea by the hypusination inhibitor N(1)-guanyl-1,7-diaminoheptane

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Biochemistry and function of hypusine formation on eukaryotic initiation factor 5A.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Hypusine is essential for eukaryotic cell proliferation.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021

Cellular eukaryotic initiation factor 5A content as a mediator of polyamine effects on growth and apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03806.X

7 January 2021