(Q24300003)

very long-chain fatty acid biosynthetic process

GOA release 2020-03-11

1 reference

X-linked adrenoleukodystrophy

GOA release 2020-03-11

1 reference

8

Ronald J A Wanders

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author name string

Rob Ofman

1

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Inge M E Dijkstra

2

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Carlo W T van Roermund

3

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Nena Burger

4

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Marjolein Turkenburg

5

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Arno van Cruchten

6

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Catherine E van Engen

7

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Stephan Kemp

The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters

9

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language of work or name

English

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publication date

March 2010

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published in

EMBO Molecular Medicine

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volume

2

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issue

3

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page(s)

90-7

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Elongation of long-chain fatty acids

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Role for ELOVL3 and fatty acid chain length in development of hair and skin function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Fatty acid elongases in mammals: their regulation and roles in metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Plasma very long chain fatty acids in 3,000 peroxisome disease patients and 29,000 controls

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Membrane microviscosity is increased in the erythrocytes of patients with adrenoleukodystrophy and adrenomyeloneuropathy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Effects of long-chain, saturated fatty acids on membrane microviscosity and adrenocorticotropin responsiveness of human adrenocortical cells in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

ELOVL2 overexpression enhances triacylglycerol synthesis in 3T3-L1 and F442A cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377275

Cholesterol-deprivation increases mono-unsaturated very long-chain fatty acids in skin fibroblasts from patients with X-linked adrenoleukodystrophy

30 May 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201000061

Lovastatin in X-linked adrenoleukodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201000061

Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201000061

Elongation of very long-chain fatty acids is enhanced in X-linked adrenoleukodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201000061

Cerebral X-linked adrenoleukodystrophy: the international hematopoietic cell transplantation experience from 1982 to 1999.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201000061

Adreno-leukodystrophy: oxidative stress of mice and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201000061

Analysis of very long-chain fatty acids using electrospray ionization mass spectrometry

21 January 2018

1 reference

12 December 2020

Adrenoleukodystrophy: evidence that abnormal very long chain fatty acids of brain cholesterol esters are of exogenous origin

1 reference

12 December 2020

Increased Synthesis of Hexacosanoic Acid (C26 :0) by Cultured Skin Fibroblasts from Patients with Adrenoleukodystrophy (ALD) and Adrenomyeloneuropathy (AMN)1

1 reference

12 December 2020

Adrenoleukodystrophy: impaired oxidation of very long chain fatty acids in white blood cells, cultured skin fibroblasts, and amniocytes

1 reference

12 December 2020

Lovastatin for X-linked adrenoleukodystrophy

1 reference

12 December 2020

Identifiers

DOI

10.1002/EMMM.201000061

1 reference

1 reference

1 reference

PubMed publication ID

20166112

1 reference