(Q24302568)

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Ghrelin enhances the growth of cultured human adrenal zona glomerulosa cells by exerting MAPK-mediated proliferogenic and antiapoptotic effects

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Ghrelin enhances the growth of cultured human adrenal zona glomerulosa cells by exerting MAPK-mediated proliferogenic and antiapoptotic effects (English)

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apoptotic process

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Ghrelin and obestatin prepropeptide

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GOA release 2020-03-11

protein tyrosine kinase activator activity

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GOA release 2020-03-11

Ludwik Malendowicz

6

object named as

Ludwik K Malendowicz

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Marcin Rucinski

3

object named as

Marcin Rucinski

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author name string

Giuseppina Mazzocchi

1

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Giuliano Neri

2

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Piera Rebuffat

4

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Raffaella Spinazzi

5

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Gastone G Nussdorfer

7

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language of work or name

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publication date

August 2004

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25

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8

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1269-77

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Tyrosine kinase-independent inhibition of cyclic-AMP phosphodiesterase by genistein and tyrphostin 51.

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Binding of 125I-labeled ghrelin to membranes from human hypothalamus and pituitary gland

1 reference

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7 January 2021

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

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Tyrphostins as molecular tools and potential antiproliferative drugs

1 reference

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Ghrelin promotes pancreatic adenocarcinoma cellular proliferation and invasiveness

1 reference

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based on heuristic

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Ghrelin in fetal thyroid and follicular tumors and cell lines: expression and effects on tumor growth

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Endothelin-1[1-31], acting as an ETA-receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ghrelin and growth hormone secretagogue receptor are expressed in the rat adrenal cortex: Evidence that ghrelin stimulates the growth, but not the secretory activity of adrenal cells

1 reference

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inferred from DOI database lookup

Ghrelin, a widespread hormone: insights into molecular and cellular regulation of its expression and mechanism of action.

1 reference

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Proadrenomedullin-derived peptides in the paracrine control of the hypothalamo-pituitary-adrenal axis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Proadrenomedullin N-terminal 20 peptide (PAMP) enhances proliferation of rat zona glomerulosa cells by activating MAPK cascade

1 reference

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inferred from DOI database lookup

The p38 signal transduction pathway: activation and function

1 reference

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based on heuristic

inferred from DOI database lookup

Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1 reference

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based on heuristic

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Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

1 reference

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

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Intracellular third loop domain of angiotensin II type-2 receptor. Role in mediating signal transduction and cellular function

1 reference

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Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

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based on heuristic

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11beta-hydroxysteroid dehydrogenase expression and activity in the human adrenal cortex

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Adrenomedullin stimulates DNA synthesis of rat adrenal zona glomerulosa cells through activation of the mitogen-activated protein kinase-dependent cascade.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

A receptor in pituitary and hypothalamus that functions in growth hormone release

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Endocrine and non-endocrine actions of ghrelin.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of protein kinases A and C pathways in the regulation of mitogen-activated protein kinase activation in response to gonadotropin-releasing hormone receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Ghrelin-induced food intake is mediated via the orexin pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclical Cushing's syndrome in a patient with a bronchial neuroendocrine tumor (typical carcinoid) expressing ghrelin and growth hormone secretagogue receptors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholecystokinin (CCK) stimulates aldosterone secretion from human adrenocortical cells via CCK2 receptors coupled to the adenylate cyclase/protein kinase A signaling cascade

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

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based on heuristic

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Pituitary adenylate-cyclase activating peptide enhances aldosterone secretion of human adrenal gland: evidence for an indirect mechanism, probably involving the local release of catecholamines

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of adrenomedullin on the human adrenal glands: an in vitro study

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Cerebellin enhances in vitro secretory activity of human adrenal gland

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification, Characterization, and Biological Activity of Specific Receptors for Natural (Ghrelin) and Synthetic Growth Hormone Secretagogues and Analogs in Human Breast Carcinomas and Cell Lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Endothelin-1[1-31]: a novel autocrine-paracrine regulator of human adrenal cortex secretion and growth

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Biologic activities of growth hormone secretagogues in humans

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Presence of ghrelin in normal and adenomatous human pituitary.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Hexarelin protects H9c2 cardiomyocytes from doxorubicin-induced cell death.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and homologous regulation of GH secretagogue receptor mRNA in rat adrenal gland

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.PEPTIDES.2004.05.011

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and action of the growth hormone releasing peptide ghrelin and its receptor in prostate cancer cell lines

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Natural (ghrelin) and synthetic (hexarelin) GH secretagogues stimulate H9c2 cardiomyocyte cell proliferation.

1 reference

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Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities

1 reference

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10.1016/J.PEPTIDES.2004.05.011

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