(Q24304218)

16 November 2016

title

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification (English)

1 reference

HECT and RLD domain containing E3 ubiquitin protein ligase 5

PubMed publication ID

16 November 2016

0 references

1 reference

regulation of defense response to virus

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

He-Xin Shi

1

0 references

Kai Yang

2

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Xing Liu

3

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Xin-Yi Liu

4

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Bo Wei

5

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Yu-Fei Shan

6

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Lian-Hui Zhu

7

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Chen Wang

Molecular and Cellular Biology

8

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language of work or name

English

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publication date

May 2010

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published in

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volume

30

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issue

10

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page(s)

2424-36

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cites work

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ISG15 inhibits Nedd4 ubiquitin E3 activity and enhances the innate antiviral response

19 March 2017

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ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP

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Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways

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Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3

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The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein

19 March 2017

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Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein

19 March 2017

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Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1

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A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor suppressor proteins

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

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ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

19 March 2017

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HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets

19 March 2017

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Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

19 March 2017

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Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells

19 March 2017

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The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase

19 March 2017

1 reference

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RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

19 March 2017

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19 March 2017

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

19 March 2017

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19 March 2017

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19 March 2017

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Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

19 March 2017

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IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

19 March 2017

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Triggering the interferon antiviral response through an IKK-related pathway

19 March 2017

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

19 March 2017

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HERC3 binding to and regulation by ubiquitin

19 March 2017

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SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

19 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

19 March 2017

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Type I interferons in host defense

19 March 2017

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

7 April 2017

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Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

7 April 2017

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Ubiquitin signalling in the NF-kappaB pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

The TAK1-JNK cascade is required for IRF3 function in the innate immune response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

Toll-like receptor and RIG-I-like receptor signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

MDA5/RIG-I and virus recognition.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

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27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

Dysregulation of protein modification by ISG15 results in brain cell injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863703

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27 September 2017

1 reference

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27 September 2017

1 reference

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29 November 2018

1 reference

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29 November 2018

1 reference

12 December 2020

Identification and Herc5-mediated ISGylation of novel target proteins

1 reference

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1 reference

12 December 2020

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1 reference

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