(Q39893547)

15 September 2017

The TAK1-JNK cascade is required for IRF3 function in the innate immune response (English)

1 reference

15 September 2017

Bianhong Zhang

1

1 reference

15 September 2017

Meng Li

2

1 reference

15 September 2017

Liang Chen

3

1 reference

15 September 2017

Kai Yang

4

1 reference

15 September 2017

Yufei Shan

5

1 reference

15 September 2017

Lianhui Zhu

6

1 reference

15 September 2017

Shaogang Sun

7

1 reference

15 September 2017

Lin Li

8

1 reference

15 September 2017

Chen Wang

9

1 reference

15 September 2017

language of work or name

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1 April 2009

1 reference

15 September 2017

1 reference

15 September 2017

19

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15 September 2017

412-428

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15 September 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/cr.2009.8

15 September 2017

0 references

cites work

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

Toll-like receptors in innate immunity

21 January 2018

1 reference

Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages.

21 January 2018

1 reference

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

Intracellular pattern recognition receptors in the host response

21 January 2018

1 reference

Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal?

21 January 2018

1 reference

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

1 reference

Toll-like receptors; their physiological role and signal transduction system

21 January 2018

1 reference

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

21 January 2018

1 reference

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

21 January 2018

1 reference

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

1 reference

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

21 January 2018

1 reference

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

21 January 2018

1 reference

Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3

21 January 2018

1 reference

Control of IRF-3 activation by phosphorylation

21 January 2018

1 reference

Analyses of virus-induced homomeric and heteromeric protein associations between IRF-3 and coactivator CBP/p300

21 January 2018

1 reference

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

21 January 2018

1 reference

Innate cellular response to virus particle entry requires IRF3 but not virus replication

21 January 2018

1 reference

Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association

21 January 2018

1 reference

Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of alpha/beta interferon

21 January 2018

1 reference

Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3.

21 January 2018

1 reference

Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways

21 January 2018

1 reference

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

21 January 2018

1 reference

Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.

21 January 2018

1 reference

Cutting edge: apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide

21 January 2018

1 reference

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta

21 January 2018

1 reference

An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK

21 January 2018

1 reference

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

21 January 2018

1 reference

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

21 January 2018

1 reference

Pharmacologic interference with NF-kappaB activation attenuates central nervous system complications in experimental Pneumococcal meningitis.

21 January 2018

1 reference

TRAF6 is a signal transducer for interleukin-1

21 January 2018

1 reference

TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

21 January 2018

1 reference

Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.

21 January 2018

1 reference

Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription

21 January 2018

1 reference

Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes

21 January 2018

1 reference

Complex modulation of cell type-specific signaling in response to type I interferons

21 January 2018

1 reference

Antiviral innate immunity pathways.

21 January 2018

1 reference

The IRF-3 transcription factor mediates Sendai virus-induced apoptosis

21 January 2018

1 reference

Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells

21 January 2018

1 reference

The interferon inducing pathways and the hepatitis C virus

21 January 2018

1 reference

Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation

21 January 2018

1 reference

Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

21 January 2018

1 reference

Zinc-binding domain of rotavirus NSP1 is required for proteasome-dependent degradation of IRF3 and autoregulatory NSP1 stability

21 January 2018

1 reference

The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes

21 January 2018

1 reference

S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway

21 January 2018

1 reference

Activation of interferon regulatory factor 3 in response to DNA-damaging agents

21 January 2018

1 reference

Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

21 January 2018

1 reference

Activation of c-Jun N-terminal kinase (JNK) pathway by HSV-1 immediate early protein ICP0.

21 January 2018

1 reference

Signal transduction through MAP kinase cascades

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Signaling pathways to the assembly of an interferon-beta enhanceosome. Chemical genetic studies with a small molecule

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CR.2009.8

1 reference

15 September 2017

1 reference