(Q24306086)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

The human DEK oncogene regulates DNA damage response signaling and repair (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

Serine and arginine rich splicing factor 2

3 February 2020

main subject

DNA damage

0 references

1 reference

GOA release 2020-03-11

DEK proto-oncogene

1 reference

DEK proto-oncogene (DNA binding)

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Trisha M Wise-Draper

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Boris Gole

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

John J Bissler

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

author name string

Gina M Kavanaugh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Richard J Morreale

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Monique A Morrison

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Sandy Schwemberger

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Elisia D Tichy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Lu Lu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

George F Babcock

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

James M Wells

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Rachid Drissi

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Peter J Stambrook

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Paul R Andreassen

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Lisa Wiesmüller

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Susanne I Wells

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

language of work or name

English

0 references

publication date

7 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

number of pages

12

1 reference

inferred from page(s)

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

page(s)

7465-7476

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

3 February 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3177200/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Amplification and overexpression of the ID4 gene at 6p22.3 in bladder cancer

1 reference

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Transcriptional activation by AP-2alpha is modulated by the oncogene DEK

19 March 2017

1 reference

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Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin-specific manner

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

19 March 2017

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Regulation of DNA double-strand break repair pathway choice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

The DEK protein--an abundant and ubiquitous constituent of mammalian chromatin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Cell-cycle checkpoints and cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

HMG1 and 2, and related 'architectural' DNA-binding proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Melanoma proliferation and chemoresistance controlled by the DEK oncogene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Proteomic analysis of apoptosis related proteins regulated by proto-oncogene protein DEK.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

DEK proto-oncogene expression interferes with the normal epithelial differentiation program.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Apoptosis inhibition by the human DEK oncoprotein involves interference with p53 functions.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

The human DEK proto-oncogene is a senescence inhibitor and an upregulated target of high-risk human papillomavirus E7

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Expression analysis of 6p22 genomic gain in retinoblastoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

p300/CBP-associated factor drives DEK into interchromatin granule clusters.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

DNA end joining becomes less efficient and more error-prone during cellular senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Defining a 0.5-mb region of genomic gain on chromosome 6p22 in bladder cancer by quantitative-multiplex polymerase chain reaction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Structure-specific binding of the proto-oncogene protein DEK to DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Gene discovery in bladder cancer progression using cDNA microarrays

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

HMG1 and 2: architectural DNA-binding proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

The identification of novel therapeutic targets for the treatment of malignant brain tumors

27 September 2017

1 reference

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Expression cloning of multiple human cDNAs that complement the phenotypic defects of ataxia-telangiectasia group D fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Functional domains of the ubiquitous chromatin protein DEK.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177200

Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemia t (15;17) patients.

30 May 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

Hypophosphorylation of the architectural chromatin protein DEK in death-receptor-induced apoptosis revealed by the isotope coded protein label proteomic platform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

Negative regulation of the RelA/p65 transactivation function by the product of the DEK proto-oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

The distribution of the DEK protein in mammalian chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

Regulation of histone acetyltransferase activity of p300 and PCAF by proto-oncogene protein DEK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

Fluorescence-based quantification of pathway-specific DNA double-strand break repair activities: a powerful method for the analysis of genome destabilizing mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

Intron Removal Requires Proofreading of U2AF/3' Splice Site Recognition by DEK

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKR454

Identification and characterization of genes associated with human hepatocellular carcinogenesis

21 January 2018

1 reference

12 December 2020

DEK Expression is controlled by E2F and deregulated in diverse tumor types

1 reference

12 December 2020

SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery

1 reference

12 December 2020

Aberrant expression of HOXA9, DEK, CBL and CSF1R in acute myeloid leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKR454

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653549%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

2 references