(Q24306149)

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Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequence

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scholarly article

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Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequence (English)

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1 reference

GOA release 2020-03-11

heparanase activity

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GOA release 2020-03-11

tumor metastasis

1 reference

based on heuristic

inferred from title

author name string

Yukihiko Okada

1

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Shuhei Yamada

2

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Minako Toyoshima

3

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Jian Dong

4

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Motowo Nakajima

5

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Kazuyuki Sugahara

6

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language of work or name

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publication date

8 November 2002

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Journal of Biological Chemistry

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277

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45

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42488-95

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Biology and pathology of the pericellular heparan sulphate proteoglycans

1 reference

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21 January 2018

Matrix proteoglycans: from molecular design to cellular function

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Functions of cell surface heparan sulfate proteoglycans

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Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions

1 reference

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Regulated diversity of heparan sulfate

1 reference

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21 January 2018

Structure and function of extracellular matrix proteoglycans

1 reference

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The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices

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Still more complexity in mammalian basement membranes

1 reference

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Heparan sulphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206510200

21 January 2018

Proteoglycans: structures and interactions

1 reference

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Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans

1 reference

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Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro.

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Developmental regulation of neural response to FGF-1 and FGF-2 by heparan sulfate proteoglycan.

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Structural comparison of fibroblast growth factor-specific heparan sulfates derived from a growing or differentiating neuroepithelial cell line

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Age-dependent modulation of heparan sulfate structure and function

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Heparanases: endoglycosidases that degrade heparan sulfate proteoglycans

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Heparan sulfate degradation: relation to tumor invasive and metastatic properties of mouse B16 melanoma sublines

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Heparanases and tumor metastasis

1 reference

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Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis

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Human heparanase. Purification, characterization, cloning, and expression

1 reference

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Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

1 reference

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Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

1 reference

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Cloning and functional expression of a human heparanase gene

1 reference

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Loss of syndecan-1 and increased expression of heparanase in invasive esophageal carcinomas.

1 reference

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Substrate specificity of heparanases from human hepatoma and platelets

1 reference

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21 January 2018

Structural studies on the tri- and tetrasaccharides isolated from porcine intestinal heparin and characterization of heparinase/heparitinases using them as substrates

1 reference

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21 January 2018

Structures of five sulfated hexasaccharides prepared from porcine intestinal heparin using bacterial heparinase. Structural variants with apparent biosynthetic precursor-product relationships for the antithrombin III-binding site

1 reference

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21 January 2018

A major common trisulfated hexasaccharide core sequence, hexuronic acid(2-sulfate)-glucosamine(N-sulfate)-iduronic acid-N-acetylglucosamine-glucuronic acid-glucosamine(N-sulfate), isolated from the low sulfated irregular region of porcine intestinal

1 reference

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21 January 2018

Structural studies of octasaccharides derived from the low-sulfated repeating disaccharide region and octasaccharide serines derived from the protein linkage region of porcine intestinal heparin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206510200

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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The Engelbreth-Holm-Swarm mouse tumor produces undersulfated heparan sulfate and oversulfated galactosaminoglycans

1 reference

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Structure and biological interactions of heparin and heparan sulfate

1 reference

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Metabolism of macromolecular heparin in mouse neoplastic mast cells

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Degradation of heparin proteoglycan in cultured mouse mastocytoma cells

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An NMR and molecular modeling study of the site-specific binding of histamine by heparin, chemically modified heparin, and heparin-derived oligosaccharides

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A strategy for rapid sequencing of heparan sulfate and heparin saccharides

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Characterization of heparanase from a rat parathyroid cell line

1 reference

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Turnover of heparan sulfate depends on 2-O-sulfation of uronic acids

1 reference

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Human platelet heparanase: purification, characterization and catalytic activity

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Partial purification of heparanase activities in Chinese hamster ovary cells: evidence for multiple intracellular heparanases

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Heparan sulfate proteoglycans in invasion and metastasis

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Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis

1 reference

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Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion

1 reference

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Processing of the human heparanase precursor and evidence that the active enzyme is a heterodimer

1 reference

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Heparanase protein and gene expression in bladder cancer

1 reference

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Structural studies on the oligosaccharides isolated from bovine kidney heparan sulphate and characterization of bacterial heparitinases used as substrates

1 reference

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Expression of three extracellular matrix degradative enzymes in bladder cancer

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Substrate specificity of the heparin lyases from Flavobacterium heparinum

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Characterization of a platelet endoglycosidase degrading heparin-like polysaccharides

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The spacing of S-domains on HS glycosaminoglycans determines whether the chain is a substrate for intracellular heparanases

1 reference

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Structural studies on heparin. Tetrasaccharides obtained by heparinase degradation

1 reference

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Heparan sulfate: a piece of information

1 reference

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7 January 2021

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10.1074/JBC.M206510200

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