(Q24306209)

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Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1

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Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1 (English)

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Solute carrier family 11 member 1

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GOA release 2020-03-11

cellular iron ion homeostasis

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GOA release 2020-03-11

David Robert Mole

object named as

David R Mole

2

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Helen J Knowles

object named as

Helen J Knowles

1

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Peter J. Ratcliffe

object named as

Peter J Ratcliffe

3

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object named as

Adrian L Harris

4

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language of work or name

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publication date

1 March 2006

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Cancer Research

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66

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5

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2600-7

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

11 October 2022

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

11 October 2022

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Expression of the human NRAMP1 gene in professional primary phagocytes: studies in blood cells and in HL-60 promyelocytic leukemia

1 reference

11 October 2022

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The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

1 reference

11 October 2022

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Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome

1 reference

11 October 2022

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Expression of HIF-1alpha by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

The natural resistance-associated macrophage protein 1 Slc11a1 (formerly Nramp1) and iron metabolism in macrophages

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

The hemochromatosis protein HFE inhibits iron export from macrophages.

1 reference

11 October 2022

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Role of ceruloplasmin in macrophage iron efflux during hypoxia

1 reference

11 October 2022

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Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms

1 reference

11 October 2022

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

1 reference

11 October 2022

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Expression and subcellular localization of NRAMP1 in human neutrophil granules

1 reference

11 October 2022

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Hypoxia--a key regulatory factor in tumour growth

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

High level expression of Nramp1G169 in RAW264.7 cell transfectants: analysis of intracellular iron transport.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Role of ascorbic acid in transferrin-independent reduction and uptake of iron by U-937 cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

The distribution of ascorbic acid between various cellular components of blood, in normal individuals, and its relation to the plasma concentration

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Fluorescence analysis of the labile iron pool of mammalian cells.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Iron uptake by human upper small intestine microvillous membrane vesicles. Indication for a facilitated transport mechanism mediated by a membrane iron-binding protein.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

The ferroportin disease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

The labile iron pool: characterization, measurement, and participation in cellular processes(1).

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

HIF-1alpha is essential for myeloid cell-mediated inflammation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

PR39, a peptide regulator of angiogenesis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

A study of intracellular iron metabolism using pyridoxal isonicotinoyl hydrazone and other synthetic chelating agents

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Ectopic expression of Nramp1 in COS-1 cells modulates iron accumulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Nramp1: a link between intracellular iron transport and innate resistance to intracellular pathogens.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Intravenous ascorbic acid as an adjuvant therapy for recombinant erythropoietin in hemodialysis patients with hyperferritinemia

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

A negative autoregulatory link between Nramp1 function and expression.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-05-2351

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

11 October 2022

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Serum carotene, vitamin A, and vitamin C levels in breast cancer and cancer of the uterine cervix

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JunD reduces tumor angiogenesis by protecting cells from oxidative stress

1 reference

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