(Q24307568)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

Platelet derived growth factor subunit B

17 January 2020

main subject

1 reference

positive regulation of DNA biosynthetic process

GOA release 2020-03-11

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GOA release 2020-03-11

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Goutam Ghosh Choudhury

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Falguni Das

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Balachandar Venkatesan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Nandini Ghosh-Choudhury

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

1 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

number of pages

11

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inferred from page(s)

published in

Cellular Signalling

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

1854-1864

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

Actions of platelet-derived growth factor isoforms in mesangial cells

17 January 2020

cites work

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7 January 2021

Bone morphogenetic protein-2 inhibits MAPK-dependent Elk-1 transactivation and DNA synthesis induced by EGF in mesangial cells

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7 January 2021

Multiple roles for Src in a PDGF-stimulated cell

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7 January 2021

Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein

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7 January 2021

Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region

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7 January 2021

Association between the PDGF receptor and members of the src family of tyrosine kinases

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7 January 2021

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

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7 January 2021

Functional analysis of a growth factor-responsive transcription factor complex

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7 January 2021

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

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7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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7 January 2021

New roles for Src kinases in control of cell survival and angiogenesis

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7 January 2021

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

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7 January 2021

Mitogen-activated protein kinase cascades and regulation of gene expression

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7 January 2021

Oncogenic kinase signalling

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7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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7 January 2021

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

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7 January 2021

PDGF-mediated activation of phosphatidylinositol 3 kinase in human mesangial cells

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7 January 2021

The interplay between Src family kinases and receptor tyrosine kinases

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7 January 2021

Electroporation-mediated PDGF receptor-IgG chimera gene transfer ameliorates experimental glomerulonephritis

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7 January 2021

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

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7 January 2021

Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol

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7 January 2021

The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor

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7 January 2021

Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogens

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7 January 2021

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat

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7 January 2021

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

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7 January 2021

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

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7 January 2021

Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

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7 January 2021

Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase

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7 January 2021

Differential modulation of G1 cyclins and the Cdk inhibitor p27kip1 by platelet-derived growth factor and plasma factors in density-arrested fibroblasts

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7 January 2021

Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

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7 January 2021

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

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7 January 2021

Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27

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7 January 2021

A role for Src in signal relay by the platelet-derived growth factor alpha receptor

1 reference

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7 January 2021

Bone morphogenetic protein 2 inhibits platelet-derived growth factor-induced c-fos gene transcription and DNA synthesis in mesangial cells. Involvement of mitogen-activated protein kinase

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7 January 2021

Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression

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7 January 2021

Akt serine threonine kinase regulates platelet-derived growth factor-induced DNA synthesis in glomerular mesangial cells: regulation of c-fos AND p27(kip1) gene expression

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7 January 2021

A linear signal transduction pathway involving phosphatidylinositol 3-kinase, protein kinase Cepsilon, and MAPK in mesangial cells regulates interferon-gamma-induced STAT1alpha transcriptional activation

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7 January 2021

Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor

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7 January 2021

Platelet-derived growth factor: mechanism of action and possible in vivo function

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7 January 2021

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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7 January 2021

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

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7 January 2021

Src family kinases are required for integrin but not PDGFR signal transduction.

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7 January 2021

Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase

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7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

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7 January 2021

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

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7 January 2021

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

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7 January 2021

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

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7 January 2021

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

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7 January 2021

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

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7 January 2021

Integration of MAP kinase signal transduction pathways at the serum response element

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7 January 2021

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

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7 January 2021

Association of type I phosphatidylinositol kinase activity with mutationally activated forms of human pp60c-src

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7 January 2021

Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types

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7 January 2021

Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

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7 January 2021

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

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7 January 2021

Activation of Src family members is not required for the platelet-derived growth factor beta receptor to initiate mitogenesis

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7 January 2021

Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.

1 reference

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7 January 2021

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

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7 January 2021

Phosphatidylinositol kinase activity associates with viral p60src protein

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7 January 2021

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

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7 January 2021

EGF stimulates mesangial cell mitogenesis via PI3-kinase-mediated MAPK-dependent and AKT kinase-independent manner: involvement of c-fos and p27Kip1

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7 January 2021

Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells

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7 January 2021

Mechanism of action and in vivo role of platelet-derived growth factor

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7 January 2021

A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling

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7 January 2021

Expression of platelet-derived growth factor receptors in normal and diseased human kidney. An immunohistochemistry and in situ hybridization study

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7 January 2021

Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes

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7 January 2021

10.1016/J.CELLSIG.2006.02.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16530387%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference