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Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
title
Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types
(English)
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
author
Wendy J. Fantl
series ordinal
2
object named as
W. J. Fantl
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
Lewis T. Williams
series ordinal
4
object named as
L. T. Williams
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
Jaime A. Escobedo
series ordinal
3
object named as
J. A. Escobedo
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
author name string
T. Satoh
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
Y. Kaziro
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
language of work or name
English
0 references
publication date
1 June 1993
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
volume
13
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
page(s)
3706–3713
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
issue
6
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
cites work
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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins
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17 March 2017
Signal transduction by the platelet-derived growth factor receptor
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17 March 2017
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro
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17 March 2017
Role of phosphatidylinositol kinase in PDGF receptor signal transduction
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17 March 2017
The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma
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Binding of GAP to activated PDGF receptors
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17 March 2017
The GTPase superfamily: a conserved switch for diverse cell functions
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17 March 2017
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17 March 2017
SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins
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17 March 2017
GTPase-activating protein interactions with the viral and cellular Src kinases
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p21rasGAP association with Fyn, Lyn, and Yes in thrombin-activated platelets
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Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma
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17 March 2017
Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae
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17 March 2017
Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21
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17 March 2017
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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17 March 2017
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
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PubMed Central
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17 March 2017
p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein
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PubMed Central
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17 March 2017
Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein
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PubMed Central
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17 March 2017
The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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17 March 2017
Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo
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PubMed Central
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17 March 2017
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
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PubMed Central
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7 April 2017
Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively
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PubMed Central
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3 June 2018
Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells
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PubMed Central
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3 June 2018
PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex.
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PubMed Central
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3 June 2018
Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity
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PubMed Central
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3 June 2018
Insulin stimulation of gene expression mediated by p21ras activation.
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PubMed Central
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3 June 2018
Insulin-induced p21ras activation does not require protein kinase C, but a protein sensitive to phenylarsine oxide.
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PubMed Central
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3 June 2018
Structure and function of signal-transducing GTP-binding proteins
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PubMed Central
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3 June 2018
Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4
1 reference
stated in
PubMed Central
reference URL
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3 June 2018
Inhibition of interleukin 3 and granulocyte-macrophage colony-stimulating factor stimulated increase of active ras.GTP by herbimycin A, a specific inhibitor of tyrosine kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Association of p21ras with phosphatidylinositol 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Regulators and Effectors of ras Proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Relation between the insulin receptor number in cells, autophosphorylation and insulin-stimulated Ras.GTP formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras
1 reference
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PubMed Central
reference URL
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3 June 2018
Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells
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PubMed Central
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3 June 2018
Involvement of p21ras in activation of extracellular signal-regulated kinase 2.
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PubMed Central
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3 June 2018
Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Erythropoietin induces p21ras activation and p120GAP tyrosine phosphorylation in human erythroleukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Ras GTPase-activating protein: a substrate and a potential binding protein of the protein-tyrosine kinase p56lck
1 reference
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PubMed Central
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3 June 2018
Nerve growth factor induces rapid accumulation of the GTP-bound form of p21ras in rat pheochromocytoma PC12 cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Activation of p21ras by transforming growth factor beta in epithelial cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Platelet-derived growth factor stimulation of GTPase-activating protein tyrosine phosphorylation in control and c-H-ras-expressing NIH 3T3 cells correlates with p21ras activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
3 June 2018
Mechanistic aspects of signaling through Ras in NIH 3T3 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
3 June 2018
Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
3 June 2018
Interleukin 2-induced activation of Ras requires two domains of interleukin 2 receptor beta subunit, the essential region for growth stimulation and Lck-binding domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Triggering signaling cascades by receptor tyrosine kinases
1 reference
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PubMed Central
reference URL
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3 June 2018
Function of Ras as a molecular switch in signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
3 June 2018
Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
3 June 2018
Oncogenic ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
3 June 2018
Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
3 June 2018
Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Stimulation of mitogen-activated protein kinase by oncogenic Ras p21 in Xenopus oocytes. Requirement for Ras p21-GTPase-activating protein interaction.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Activation of the colony-stimulating factor 1 receptor leads to the rapid tyrosine phosphorylation of GTPase-activating protein and activation of cellular p21ras
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
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3 June 2018
Stimulation of p21 ras upon T-cell activation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359844
retrieved
27 November 2018
Cytokine receptors and signal transduction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8388543
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
NGF and EGF rapidly activate p21ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8388543
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8388543
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Binding of the h-ras p21 GTPase activating protein by the activated epidermal growth factor receptor leads to inhibition of the p21 GTPase activity in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8388543
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.13.6.3706
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PMCID
359844
0 references
PubMed ID
8388543
1 reference
stated in
PubMed
PubMed ID
8388543
retrieved
3 February 2017
ResearchGate publication ID
14809850
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