(Q24307756)

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Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes

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Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes (English)

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author name string

Koichi Misawa

1

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Taro Horiba

2

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Naoto Arimura

3

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Yuko Hirano

4

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Jun Inoue

5

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Noriaki Emoto

6

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Hitoshi Shimano

7

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Makoto Shimizu

8

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Ryuichiro Sato

9

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language of work or name

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publication date

19 September 2003

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Journal of Biological Chemistry

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278

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38

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36176-82

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

1 reference

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Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway

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Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway

1 reference

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Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

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Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

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Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

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Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins

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Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

1 reference

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Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.

1 reference

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Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis

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Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast

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Mutations in a delta 8-delta 7 sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata. jderry@immunex.com

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Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA.

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Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2.

1 reference

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Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

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Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins

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Multiple sequence elements are involved in the transcriptional regulation of the human squalene synthase gene

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Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase

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Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene

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Acetylation regulates transcription factor activity at multiple levels

1 reference

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Serine/threonine phosphorylation of orphan receptor hepatocyte nuclear factor 4.

1 reference

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Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

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The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

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Sterol regulatory element-binding protein-1 interacts with the nuclear thyroid hormone receptor to enhance acetyl-CoA carboxylase-alpha transcription in hepatocytes

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SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein

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CBP is required for sterol-regulated and sterol regulatory element-binding protein-regulated transcription

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The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB)

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Metabolism. Controlling the glucose factory

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Activation of PPARgamma coactivator-1 through transcription factor docking

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

1 reference

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Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions

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Identifiers

10.1074/JBC.M302387200

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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