(Q24309618)

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Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases

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scholarly article

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Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases (English)

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Diacylglycerol kinase delta

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GOA release 2020-03-11

signal transduction

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GOA release 2020-03-11

object named as

I Wada

4

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object named as

F Sakane

1

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author name string

S Imai

2

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M Kai

3

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H Kanoh

5

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language of work or name

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publication date

5 April 1996

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Journal of Biological Chemistry

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271

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14

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8394-401

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Diacylglycerol kinase: a key modulator of signal transduction?

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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A cytoplasmic protein inhibits the GTPase activity of H-Ras in a phospholipid-dependent manner

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Phosphatidylcholine breakdown and signal transduction

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Diacylglycerol kinase and phosphatidic acid phosphatase--enzymes metabolizing lipid second messengers.

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A diacylglycerol kinase is involved in the regulation of interleukin-2 synthesis in Jurkat T cells

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Drosophila retinal degeneration A gene encodes an eye-specific diacylglycerol kinase with cysteine-rich zinc-finger motifs and ankyrin repeats.

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Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol

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Porcine diacylglycerol kinase sequence has zinc finger and E-F hand motifs.

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Purification, cDNA-cloning and expression of human diacylglycerol kinase

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Gene cloning, sequence, expression and in situ localization of 80 kDa diacylglycerol kinase specific to oligodendrocyte of rat brain

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Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localizes in neurons

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Cloning and expression of a cytoskeleton-associated diacylglycerol kinase that is dominantly expressed in cerebellum

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Molecular cloning of a Drosophila diacylglycerol kinase gene that is expressed in the nervous system and muscle.

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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

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DNA sequencing with chain-terminating inhibitors

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Improved tools for biological sequence comparison

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Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

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The regulatory role of EF-hand motifs of pig 80K diacylglycerol kinase as assessed using truncation and deletion mutants.

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High-efficiency cloning of full-length cDNA; construction and screening of cDNA expression libraries for mammalian cells

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Use of T7 RNA polymerase to direct expression of cloned genes

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

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Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene

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Pleckstrin domain homology

1 reference

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The PH domain: a common piece in the structural patchwork of signalling proteins

1 reference

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PH domain: the first anniversary

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Molecular cloning and expression of the major protein kinase C substrate of platelets

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A novel putative tyrosine kinase receptor encoded by the eph gene

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cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases

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Characterization of elk, a brain-specific receptor tyrosine kinase

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Molecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines

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Identification of a complete Cek7 receptor protein tyrosine kinase coding sequence and cDNAs of alternatively spliced transcripts.

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Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

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Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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B61 is a ligand for the ECK receptor protein-tyrosine kinase

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Protein kinase recognition sequence motifs

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The P-loop--a common motif in ATP- and GTP-binding proteins

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The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding

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Protein kinase C epsilon is localized to the Golgi via its zinc-finger domain and modulates Golgi function

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

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Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

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The role of protein kinase C in cell surface signal transduction and tumour promotion

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Identification of chicken embryo kinase 5, a developmentally regulated receptor-type tyrosine kinase of the Eph family

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SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat

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