(Q24314325)

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Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

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scholarly article

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Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks (English)

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protein structure

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Ubiquitin conjugating enzyme E2 B

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GOA release 2020-03-11

RAD18 E3 ubiquitin protein ligase

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GOA release 2020-03-11

ubiquitin protein ligase binding

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GOA release 2020-03-11

author name string

Yuri Tsuji

1

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Kenji Watanabe

2

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Kimi Araki

3

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Masanori Shinohara

4

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Yuriko Yamagata

5

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Toshiki Tsurimoto

6

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Fumio Hanaoka

7

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Ken-Ichi Yamamura

8

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Masaru Yamaizumi

9

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Satoshi Tateishi

10

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language of work or name

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publication date

April 2008

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13

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4

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343-54

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SAP - a putative DNA-binding motif involved in chromosomal organization

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

hRAD30 mutations in the variant form of xeroderma pigmentosum

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Gaps and forks in DNA replication: Rediscovering old models

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Regulated expression and dynamic changes in subnuclear localization of mammalian Rad18 under normal and genotoxic conditions

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

https://api.crossref.org/works/10.1111/J.1365-2443.2008.01176.X

20 April 2017

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

20 April 2017

Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

20 April 2017

The role of the SAP motif in promoting Holliday junction binding and resolution by SpCCE1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Domains required for dimerization of yeast Rad6 ubiquitin-conjugating enzyme and Rad18 DNA binding protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Postreplication repair and PCNA modification in Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Replication-dependent and -independent responses of RAD18 to DNA damage in human cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

A central role for DNA replication forks in checkpoint activation and response

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

21 January 2018

Novel endonuclease in Archaea cleaving DNA with various branched structure

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2008.01176.X

7 January 2021

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