(Q24315127)

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Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells

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Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells (English)

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Glycogen synthase kinase 3 alpha

1 reference

GOA release 2020-03-11

insulin receptor signaling pathway

1 reference

GOA release 2020-03-11

Glycogen synthase kinase 3 alpha

1 reference

GOA release 2020-03-11

Protein kinase C, delta

1 reference

GOA release 2020-03-11

phosphorylation

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

skeletal muscle cell

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based on heuristic

inferred from title

Hubert Kalbacher

3

object named as

Hubert Kalbacher

author given names

Hubert

author last names

Kalbacher

1 reference

PubMed publication ID

20 April 2024

Hans-Ulrich Häring

6

object named as

Hans-Ulrich Häring

author given names

Hans-Ulrich

author last names

Häring

1 reference

PubMed publication ID

20 April 2024

2

object named as

Cora Weigert

author given names

Cora

author last names

Weigert

1 reference

PubMed publication ID

20 April 2024

Erwin Schleicher

7

object named as

Erwin D Schleicher

author given names

Erwin D

author last names

Schleicher

1 reference

PubMed publication ID

20 April 2024

author name string

Rizwana Sanaullah Waraich

1

author given names

Rizwana Sanaullah

author last names

Waraich

1 reference

PubMed publication ID

20 April 2024

Anita M Hennige

4

author given names

Anita M

author last names

Hennige

1 reference

PubMed publication ID

20 April 2024

Stefan Z Lutz

5

author given names

Stefan Z

author last names

Lutz

1 reference

PubMed publication ID

20 April 2024

Wolfgang Voelter

8

author given names

Wolfgang

author last names

Voelter

1 reference

PubMed publication ID

20 April 2024

Rainer Lehmann

9

author given names

Rainer

author last names

Lehmann

1 reference

PubMed publication ID

20 April 2024

language of work or name

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publication date

25 April 2008

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Journal of Biological Chemistry

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283

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17

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11226-33

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Critical nodes in signalling pathways: insights into insulin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

The phosphorylation of Ser318 of insulin receptor substrate 1 is not per se inhibitory in skeletal muscle cells but is necessary to trigger the attenuation of the insulin-stimulated signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Knockout of PKC alpha enhances insulin signaling through PI3K

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

PKC-theta knockout mice are protected from fat-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Specific protein kinase C isoforms as transducers and modulators of insulin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Protein kinase Cdelta mediates insulin-induced glucose transport in primary cultures of rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Physical exercise enhances protein kinase C delta activity and insulin receptor tyrosine phosphorylation in diabetes-prone psammomys obesus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Insulin induces specific interaction between insulin receptor and protein kinase C delta in primary cultured skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Differential effects of tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Identification of an in vitro insulin receptor substrate-1 phosphorylation site by negative-ion muLC/ES-API-CID-MS hybrid scan technique

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Role of glycogen synthase kinase-3 alpha in insulin action in cultured human skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

21 January 2018

Protein kinase Cdelta participates in insulin-induced activation of PKB via PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

7 January 2021

based on heuristic

inferred from DOI database lookup

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708588200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M708588200

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release_pszdfa5upvfxvdmpjpztkns5ea

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