(Q24315151)

metalloendopeptidase inhibitor activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Klaus Maskos

3

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Peter Goettig

2

object named as

Peter Goettig

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Wolfram Bode

8

object named as

Wolfram Bode

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author name string

Magdalena Wisniewska

1

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Edward Belouski

4

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Dwight Winters

5

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Randy Hecht

6

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Roy Black

Journal of Molecular Biology

7

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language of work or name

English

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publication date

19 September 2008

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published in

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volume

381

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issue

5

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page(s)

1307-19

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cites work

OB(oligonucleotide/oligosaccharide binding)-fold: common structural and functional solution for non-homologous sequences

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structure of RVV-X: an example of evolutionary gain of specificity by ADAM proteinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structure of the catalytic domain of human ADAM33

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4)

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Tissue inhibitors of metalloproteinases: evolution, structure and function

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A)

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Therapeutic benefits from targeting of ADAM family members

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Catalytic properties of ADAM12 and its domain deletion mutants

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

ADAMs: key components in EGFR signalling and development

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Tailoring tissue inhibitor of metalloproteinases-3 to overcome the weakening effects of the cysteine-rich domains of tumour necrosis factor-alpha converting enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Engineering N-terminal domain of tissue inhibitor of metalloproteinase (TIMP)-3 to be a better inhibitor against tumour necrosis factor-alpha-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Localization of the functional domains of human tissue inhibitor of metalloproteinases-3 and the effects of a Sorsby's fundus dystrophy mutation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Residue 2 of TIMP-1 is a major determinant of affinity and specificity for matrix metalloproteinases but effects of substitutions do not correlate with those of the corresponding P1' residue of substrate

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Reactive site-modified tissue inhibitor of metalloproteinases-2 inhibits the cell-mediated activation of progelatinase A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Human tissue inhibitor of metalloproteinases 3 interacts with both the N- and C-terminal domains of gelatinases A and B. Regulation by polyanions

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Biophysical and functional characterization of full-length, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli. Comparison of wild type and amino-terminal alanine appended variant with implications for t

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzyme

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5)

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-alpha-converting enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Unveiling the surface epitopes that render tissue inhibitor of metalloproteinase-1 inactive against membrane type 1-matrix metalloproteinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Threonine 98, the pivotal residue of tissue inhibitor of metalloproteinases (TIMP)-1 in metalloproteinase recognition

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Identification of the extracellular matrix (ECM) binding motifs of tissue inhibitor of metalloproteinases (TIMP)-3 and effective transfer to TIMP-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2)

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

MEROPS: the peptidase database

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

MOLREP: an Automated Program for Molecular Replacement

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

xdlMAPMAN and xdlDATAMAN - programs for reformatting, analysis and manipulation of biomacromolecular electron-density maps and reflection data sets

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Mapping and characterization of the functional epitopes of tissue inhibitor of metalloproteinases (TIMP)-3 using TIMP-1 as the scaffold: a new frontier in TIMP engineering

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

An essential role for ectodomain shedding in mammalian development

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3).

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Accelerated apoptosis in the Timp-3-deficient mammary gland

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021

Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2008.06.088

7 January 2021