(Q24316173)

English

Neuroprotection of insulin against oxidative stress-induced apoptosis in cultured retinal neurons: involvement of phosphoinositide 3-kinase/Akt signal pathway

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scholarly article

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Neuroprotection of insulin against oxidative stress-induced apoptosis in cultured retinal neurons: involvement of phosphoinositide 3-kinase/Akt signal pathway (English)

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apoptotic process

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AKT serine/threonine kinase 1

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GOA release 2020-03-11

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

Xiao-Rui Yu

1

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Guo-Rong Jia

2

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Guang-Dao Gao

3

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Shu-Hong Wang

4

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Yan Han

5

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Wei Cao

6

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language of work or name

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publication date

April 2006

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Acta Biochimica et Biophysica Sinica

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38

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241-8

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4

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TUNEL-positive ganglion cells in human primary open-angle glaucoma.

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Oxidative stress, antioxidant defences and aging.

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Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase pathways

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Pigment epithelium-derived factor protects cultured retinal neurons against hydrogen peroxide-induced cell death.

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Recoverin negative photoreceptor cells

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Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells.

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Photoreceptor decay over time and apoptosis in experimental retinal detachment

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Effects of astrocytes, insulin and insulin-like growth factor I on the survival of motoneurons in vitro

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Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

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The effect of insulin and insulin-like growth factor-1 on the expression of calretinin and calbindin D-28k in rat embryonic neurons in culture

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The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation

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Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

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Insulin affects synaptosomal GABA and glutamate transport under oxidative stress conditions

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Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu

1 reference

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Retinal ischemia leads to apoptosis which is ameliorated by aurintricarboxylic acid

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Sustained phosphorylation and activation of protein kinase B correlates with brain-derived neurotrophic factor and insulin stimulated survival of cerebellar granule cells.

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Apoptotic process in the monkey small intestinal epithelium: 2. Possible role of oxidative stress

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Apoptotic cell death in retinal degenerations.

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Brain insulin: regulation, mechanisms of action and functions

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Regulation by insulin of a unique neuronal Ca2+ pool and of neuropeptide secretion

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Evidence for two apoptotic pathways in light-induced retinal degeneration

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Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors

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Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.

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Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

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Mechanisms of cell death in the inherited retinal degenerations

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Hydrogen peroxide-induced motoneuron apoptosis is prevented by poly ADP ribosyl synthetase inhibitors

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Reactive oxygen species and the central nervous system

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

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The phosphoinositide 3-kinase pathway

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Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

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A morphometric study of light-induced damage in transgenic rat models of retinitis pigmentosa

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Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin

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Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid

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Identifiers

10.1111/J.1745-7270.2006.00152.X

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