(Q24317058)

20 October 2023

5

Francis Schaeffer

Francis

Schaeffer

1 reference

20 October 2023

Ricardo M Biondi

14

Ricardo M

Biondi

1 reference

20 October 2023

Pedro M Alzari

11

Pedro M

Alzari

1 reference

20 October 2023

4

Adriana Stroba

Adriana

Stroba

1 reference

20 October 2023

8

Leila Idrissova

Leila

Idrissova

1 reference

20 October 2023

9

Wolfgang Nastainczyk

Wolfgang

Nastainczyk

1 reference

20 October 2023

13

Albrecht Piiper

Albrecht

Piiper

1 reference

20 October 2023

2

Valerie Hindie

Valerie

Hindie

1 reference

20 October 2023

Matthias Engel

1

Matthias

Engel

1 reference

20 October 2023

Laura A Lopez-Garcia

3

Laura A

Lopez-Garcia

1 reference

20 October 2023

Iris Adrian

6

Iris

Adrian

1 reference

20 October 2023

Jochen Imig

7

Jochen

Imig

1 reference

20 October 2023

Rolf W Hartmann

12

Rolf W

Hartmann

1 reference

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

20 October 2023

language of work or name

English

0 references

publication date

29 November 2006

0 references

published in

The EMBO Journal

0 references

volume

25

0 references

issue

23

0 references

page(s)

5469-80

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Crystal structure of an inactive Akt2 kinase domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

The conformational plasticity of protein kinases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Oncogenic kinase signalling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Crystal structure of the Src family tyrosine kinase Hck

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Three-dimensional structure of the tyrosine kinase c-Src

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Protein kinases--the major drug targets of the twenty-first century?

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

In vivo role of the phosphate groove of PDK1 defined by knockin mutation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

The structure of MSK1 reveals a novel autoinhibitory conformation for a dual kinase protein.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Phosphoinositide-dependent protein kinase 1, a sensor of protein conformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Regulation of protein kinases in insulin, growth factor and Wnt signalling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Structural basis for control by phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

AGC protein kinase phosphorylation and protein kinase C.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Crystallization studies of cAMP-dependent protein kinase. Cocrystals of the catalytic subunit with a 20 amino acid residue peptide inhibitor and MgATP diffract to 3.0 A resolution

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Protein phosphorylation in signaling--50 years and counting

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Catalytic domain crystal structure of protein kinase C-theta (PKCtheta).

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

Duplicated dockerin subdomains of Clostridium thermocellum endoglucanase CelD bind to a cohesin domain of the scaffolding protein CipA with distinct thermodynamic parameters and a negative cooperativity

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679772

The Catalytic Subunit of Dictyostelium cAMP-Dependent Protein Kinase. Role of the N-Terminal Domain and of the C-Terminal Residues in Catalytic Activity and Stability

29 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17110931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7601416

0 references

Fatcat ID

release_r5iuyis7cndrbjuf5fod7hgpuu

0 references

PMC publication ID

1679772

0 references